Strong efforts made to do something difficult. To try very hard to do something difficult.

From one end or side of something to the other. From the beginning of something until the end. Over, in, across an entire thing or place.

Concerning the cranium which encloses the brain.

state of something. Diseases or other medical problems. have significant influence on.

Creating interest, happiness or pleasurable fear. To make someone feel happy, interested or eager.

situated on or near outside. situated beyond boundaries of place. Area around or near something, such as a building. situated beyond boundaries of.

Effort made to try to do or accomplish something. make effort to do.

cause, explanation, or justification for action or event. Explanations for why some things occurred or was done. think, understand, and form judgements logically.

talk about something with person or people.

abbreviation formed from initial letters of other words.

act of moving.

physical or mental condition that limits person's movements or activities. Conditions limiting your abilities to do some things.

physical or mental feature which is regarded as indicating condition of disease. Signs that suggests that there are problems.

Made by intertwining threads in a series of loops. To join or be joined closely together.

used for emphasis with following adjective functioning as adverb. Thing that is not yet known or named.