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  • 00:04

    So you're a scientist, and ...
    So you're a scientist, and ...

  • 00:07

    somewhere along the way, hammered into your head
    somewhere along the way, hammered into your head

  • 00:10

    is the inevitable “nature versus nurture”
    is the inevitable “nature versus nurture”

  • 00:13

    and that's at least up there with Coke versus Pepsi
    and that's at least up there with Coke versus Pepsi

  • 00:16

    or Greeks versus Trojans.
    or Greeks versus Trojans.

  • 00:18

    So, nature versus nurture: This, by now
    So, nature versus nurture: This, by now

  • 00:21

    utterly over-simplifying view of
    utterly over-simplifying view of

  • 00:24

    where influences are-
    where influences are-

  • 00:26

    influences on how a cell deals with
    influences on how a cell deals with

  • 00:31

    an energy crisis up to
    an energy crisis up to

  • 00:33

    what makes us who we are on the most individualistic
    what makes us who we are on the most individualistic

  • 00:36

    levels of personality.
    levels of personality.

  • 00:39

    And what you've got is this complete false dichotomy
    And what you've got is this complete false dichotomy

  • 00:42

    built around nature as deterministic
    built around nature as deterministic

  • 00:45

    at the very bottom of all the causality.
    at the very bottom of all the causality.

  • 00:48

    Of 'life is DNA' and the 'code of codes'
    Of 'life is DNA' and the 'code of codes'

  • 00:51

    and the Holy Grail, and everything is driven by it.
    and the Holy Grail, and everything is driven by it.

  • 00:54

    At the other end is a much more social science perspective
    At the other end is a much more social science perspective

  • 00:57

    which is: We are 'social organisms'
    which is: We are 'social organisms'

  • 01:00

    and biology is for slime molds;
    and biology is for slime molds;

  • 01:03

    humans are free of biology.
    humans are free of biology.

  • 01:06

    And obviously both views are nonsense.
    And obviously both views are nonsense.

  • 01:09

    What you see instead is that
    What you see instead is that

  • 01:11

    it is virtually impossible to understand how biology works
    it is virtually impossible to understand how biology works

  • 01:16

    outside of the context of environment.
    outside of the context of environment.

  • 01:19

    [ It's Genetic ]
    [ It's Genetic ]

  • 01:21

    One of the most crazy making yet widespread
    One of the most crazy making yet widespread

  • 01:26

    and potentially dangerous notions is:
    and potentially dangerous notions is:

  • 01:29

    “Oh, that behavior is genetic.”
    “Oh, that behavior is genetic.”

  • 01:33

    Now what does that mean? It means all sorts of subtle stuff if you
    Now what does that mean? It means all sorts of subtle stuff if you

  • 01:37

    know modern biology, but for most people out there
    know modern biology, but for most people out there

  • 01:40

    what it winds up meaning is:
    what it winds up meaning is:

  • 01:42

    a deterministic view of life,
    a deterministic view of life,

  • 01:45

    one rooted in biology and genetics.
    one rooted in biology and genetics.

  • 01:48

    Genes equal things that can't be changed.
    Genes equal things that can't be changed.

  • 01:51

    Genes equal things that are
    Genes equal things that are

  • 01:54

    inevitable and that you might as well
    inevitable and that you might as well

  • 01:56

    not waste resources trying to fix,
    not waste resources trying to fix,

  • 01:59

    might as well not put societal energies into trying to improve
    might as well not put societal energies into trying to improve

  • 02:02

    because it's inevitable and it's unchangeable.
    because it's inevitable and it's unchangeable.

  • 02:05

    And that is sheer nonsense.
    And that is sheer nonsense.

  • 02:11

    [ Disease ]
    [ Disease ]

  • 02:14

    It is widely thought that
    It is widely thought that

  • 02:17

    conditions like ADHD are genetically programmed,
    conditions like ADHD are genetically programmed,

  • 02:20

    conditions like schizophrenia are genetically programmed.
    conditions like schizophrenia are genetically programmed.

  • 02:22

    The truth is the opposite. Nothing is genetically programmed.
    The truth is the opposite. Nothing is genetically programmed.

  • 02:26

    There are very rare diseases, a small handful,
    There are very rare diseases, a small handful,

  • 02:29

    extremely sparsely represented in the population,
    extremely sparsely represented in the population,

  • 02:33

    that are truly genetically determined.
    that are truly genetically determined.

  • 02:37

    Most complex conditions
    Most complex conditions

  • 02:39

    might have a predisposition that has a genetic component,
    might have a predisposition that has a genetic component,

  • 02:43

    but a predisposition is not the same as a predetermination.
    but a predisposition is not the same as a predetermination.

  • 02:47

    The whole search for the source of diseases in the genome
    The whole search for the source of diseases in the genome

  • 02:51

    was doomed to failure before anybody even thought of it,
    was doomed to failure before anybody even thought of it,

  • 02:54

    because most diseases are not genetically predetermined.
    because most diseases are not genetically predetermined.

  • 02:58

    Heart disease, cancer, strokes,
    Heart disease, cancer, strokes,

  • 03:02

    rheumatoid conditions, autoimmune conditions in general,
    rheumatoid conditions, autoimmune conditions in general,

  • 03:07

    mental health conditions, addictions-
    mental health conditions, addictions-

  • 03:09

    none of them are genetically determined.
    none of them are genetically determined.

  • 03:12

    Breast cancer, for example. Out of 100 women with breast cancer
    Breast cancer, for example. Out of 100 women with breast cancer

  • 03:16

    only seven will carry the breast cancer genes.
    only seven will carry the breast cancer genes.

  • 03:19

    93 do not.
    93 do not.

  • 03:21

    And out of 100 women who do have the genes
    And out of 100 women who do have the genes

  • 03:23

    not all of them will get cancer.
    not all of them will get cancer.

  • 03:28

    [ Behavior ]
    [ Behavior ]

  • 03:30

    Genes are not just things that make us behave in
    Genes are not just things that make us behave in

  • 03:33

    a particular way regardless of our environment.
    a particular way regardless of our environment.

  • 03:38

    Genes give us different ways of responding to our environment.
    Genes give us different ways of responding to our environment.

  • 03:42

    And in fact it looks as if some of the early
    And in fact it looks as if some of the early

  • 03:46

    childhood influences and the kind of child rearing,
    childhood influences and the kind of child rearing,

  • 03:51

    affect gene expression:
    affect gene expression:

  • 03:52

    actually turning on or off different genes
    actually turning on or off different genes

  • 03:55

    to put you on a different developmental track
    to put you on a different developmental track

  • 03:59

    which may suit the kind of world you've got to deal with.
    which may suit the kind of world you've got to deal with.

  • 04:03

    So for example,
    So for example,

  • 04:04

    a study done in Montreal with suicide victims
    a study done in Montreal with suicide victims

  • 04:09

    looked at autopsies of the brains of these people.
    looked at autopsies of the brains of these people.

  • 04:12

    And it turned out that if a suicide victim
    And it turned out that if a suicide victim

  • 04:15

    (these are usually young adults)
    (these are usually young adults)

  • 04:17

    had been abused as children, the abuse actually
    had been abused as children, the abuse actually

  • 04:20

    caused a genetic change in the brain
    caused a genetic change in the brain

  • 04:23

    that was absent in the brains of people who had not been abused.
    that was absent in the brains of people who had not been abused.

  • 04:28

    That's an epigenetic effect.
    That's an epigenetic effect.

  • 04:29

    “Epi” means on top of, so that
    “Epi” means on top of, so that

  • 04:32

    the epigenetic influence is what happens
    the epigenetic influence is what happens

  • 04:36

    environmentally to either activate or deactivate certain genes.
    environmentally to either activate or deactivate certain genes.

  • 04:42

    In New Zealand, there was a study
    In New Zealand, there was a study

  • 04:44

    that was done in a town called Dunedin,
    that was done in a town called Dunedin,

  • 04:47

    in which a few thousand individuals
    in which a few thousand individuals

  • 04:52

    were studied from birth into their 20s.
    were studied from birth into their 20s.

  • 04:56

    What they found was that they could identify
    What they found was that they could identify

  • 05:02

    a genetic mutation- an abnormal gene-
    a genetic mutation- an abnormal gene-

  • 05:05

    which did have some relation to
    which did have some relation to

  • 05:08

    the predisposition to commit violence,
    the predisposition to commit violence,

  • 05:12

    but only if the individual had also
    but only if the individual had also

  • 05:15

    been subjected to severe child abuse.
    been subjected to severe child abuse.

  • 05:19

    In other words, children with this abnormal gene
    In other words, children with this abnormal gene

  • 05:22

    would be no more likely to be violent than anybody else,
    would be no more likely to be violent than anybody else,

  • 05:25

    and in fact, they actually had a lower rate of violence
    and in fact, they actually had a lower rate of violence

  • 05:28

    than people with normal genes
    than people with normal genes

  • 05:30

    as long as they weren't abused as children.
    as long as they weren't abused as children.

  • 05:34

    Great additional example of the ways
    Great additional example of the ways

  • 05:36

    in which genes are not “be all - end all.”
    in which genes are not “be all - end all.”

  • 05:38

    A fancy technique where you can
    A fancy technique where you can

  • 05:40

    take a specific gene out of a mouse,
    take a specific gene out of a mouse,

  • 05:43

    that mouse and its descendants will not have that gene.
    that mouse and its descendants will not have that gene.

  • 05:45

    You have ”knocked out” that gene.
    You have ”knocked out” that gene.

  • 05:47

    So there's this one gene that encodes for a protein
    So there's this one gene that encodes for a protein

  • 05:49

    that has something to do with learning and memory.
    that has something to do with learning and memory.

  • 05:52

    And with this fabulous demonstration you “knock out” that gene
    And with this fabulous demonstration you “knock out” that gene

  • 05:56

    and you have a mouse that doesn't learn as well.
    and you have a mouse that doesn't learn as well.

  • 05:58

    “Ooh! A genetic basis for intelligence!”
    “Ooh! A genetic basis for intelligence!”

  • 06:01

    What was much less appreciated in that landmark study
    What was much less appreciated in that landmark study

  • 06:04

    that got picked up by the media left and right,
    that got picked up by the media left and right,

  • 06:07

    is take those genetically impaired mice
    is take those genetically impaired mice

  • 06:10

    and raise them in a much more enriched
    and raise them in a much more enriched

  • 06:12

    stimulating environment than your normal mice in a lab cage,
    stimulating environment than your normal mice in a lab cage,

  • 06:15

    and they completely overcame that deficit.
    and they completely overcame that deficit.

  • 06:19

    So, when one says in a contemporary sense that
    So, when one says in a contemporary sense that

  • 06:23

    “Oh, this behavior is genetic”
    “Oh, this behavior is genetic”

  • 06:26

    to the extent that that's even a valid sort of phrase to use,
    to the extent that that's even a valid sort of phrase to use,

  • 06:29

    what you're saying is: there is a
    what you're saying is: there is a

  • 06:32

    genetic contribution to how this organism responds to environment;
    genetic contribution to how this organism responds to environment;

  • 06:37

    genes may influence the readiness with which
    genes may influence the readiness with which

  • 06:41

    an organism will deal with a certain environmental challenge.
    an organism will deal with a certain environmental challenge.

  • 06:44

    You know, that's not the version most people have in their minds.
    You know, that's not the version most people have in their minds.

  • 06:47

    And not to be too 'soap-boxing'
    And not to be too 'soap-boxing'

  • 06:50

    but run with the old version of “It's genetic!” and
    but run with the old version of “It's genetic!” and

  • 06:55

    it's not that far from the history of Eugenics and things of that sort.
    it's not that far from the history of Eugenics and things of that sort.

  • 07:00

    It's a widespread misconception
    It's a widespread misconception

  • 07:02

    and it's a potentially fairly dangerous one.
    and it's a potentially fairly dangerous one.

  • 07:05

    One reason that the
    One reason that the

  • 07:09

    biological explanation for violence,
    biological explanation for violence,

  • 07:11

    one reason that hypothesis is potentially dangerous-
    one reason that hypothesis is potentially dangerous-

  • 07:15

    it's not just misleading it can really do harm-
    it's not just misleading it can really do harm-

  • 07:19

    is because if you believe that, you could very easily say:
    is because if you believe that, you could very easily say:

  • 07:23

    “Well, there's nothing we can do
    “Well, there's nothing we can do

  • 07:26

    to change the predisposition people have to becoming violent.
    to change the predisposition people have to becoming violent.

  • 07:30

    All we can do, if somebody becomes violent is
    All we can do, if somebody becomes violent is

  • 07:33

    punish them- lock them up or execute them-
    punish them- lock them up or execute them-

  • 07:36

    but we don't need to worry about changing the
    but we don't need to worry about changing the

  • 07:39

    social environment or the social preconditions
    social environment or the social preconditions

  • 07:43

    that may lead people to become violent
    that may lead people to become violent

  • 07:46

    because that's irrelevant.”
    because that's irrelevant.”

  • 07:49

    The genetic argument allows us the luxury of ignoring
    The genetic argument allows us the luxury of ignoring

  • 07:53

    past and present historical and social factors.
    past and present historical and social factors.

  • 07:56

    And in the words of Louis Menand
    And in the words of Louis Menand

  • 07:59

    who wrote in the New Yorker, very astutely he said:
    who wrote in the New Yorker, very astutely he said:

  • 08:02

    “It's all in the genes, an explanation for the way things are
    “It's all in the genes, an explanation for the way things are

  • 08:06

    that does not threaten the way things are.
    that does not threaten the way things are.

  • 08:09

    Why should someone feel unhappy or
    Why should someone feel unhappy or

  • 08:12

    engage in antisocial behavior when that person is living
    engage in antisocial behavior when that person is living

  • 08:16

    in the freest and most prosperous nation on Earth?
    in the freest and most prosperous nation on Earth?

  • 08:19

    It can't be the system.
    It can't be the system.

  • 08:21

    There must be a flaw in the wiring somewhere.”
    There must be a flaw in the wiring somewhere.”

  • 08:24

    Which is a good way of putting it.
    Which is a good way of putting it.

  • 08:26

    So, the genetic argument is simply a cop-out
    So, the genetic argument is simply a cop-out

  • 08:30

    which allows us to ignore
    which allows us to ignore

  • 08:32

    the social and economic and political factors
    the social and economic and political factors

  • 08:35

    that, in fact, underlie many troublesome behaviors.
    that, in fact, underlie many troublesome behaviors.

All adverb
so
/sō/

word

to such great extent

Moving Forward - The Genetic Argument

4,399 views

Video Language:

  • english

Caption Language:

  • English (en)

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Intro:

So you're a scientist, and .... somewhere along the way, hammered into your head. is the inevitable “nature versus nurture”. and that's at least up there with Coke versus Pepsi
or Greeks versus Trojans.. So, nature versus nurture: This, by now. utterly over-simplifying view of. where influences are-. influences on how a cell deals with. an energy crisis up to. what makes us who we are on the most individualistic
levels of personality.. And what you've got is this complete false dichotomy
built around nature as deterministic. at the very bottom of all the causality.. Of 'life is DNA' and the 'code of codes'. and the Holy Grail, and everything is driven by it.
At the other end is a much more social science perspective
which is: We are 'social organisms'. and biology is for slime molds;.

Video Vocabulary