welcome to another MedCram Covid nineteen update total confirmed cases
ninety six thousand total deaths 3300 total recovered fifty three thousands
going over to the world ometer site total cases were leveling off now
starting to pick up we are definitely in the epidemic face here outside of china
i like to go to the world ometer for the latest updates which is on the home page
and you can see here for March 5th and of course the day is not done just
beginning two new cases here in the United States four new cases in Thailand
a hundred and forty five new cases in South Korea they are testing
aggressively in South Korea as you can see and if you look at the completed day
four yesterday you will see two new deaths in the United States and 34 new
cases here as well the West Coast is the place where the epidemic is occurring
most we have twelve new cases in Washington State and twelve new cases in
California five hundred and eighty seven new cases in just one day in Italy with
twenty eight new deaths if we look at the worldwide closed cases we can see
that the death rate is still falling as the virus progresses death rate falling
under six percent we know that the w-h-o yesterday declared that the world's wide
estimated case fatality rate is somewhere at the three percent range
they had previously said around two percents looking at active cases that
are going on right now there about 38,000 of those 32,000 are in mild
condition probably don't even need to be in the hospital seventeen percent are in
serious or critical condition these are people in the hospital or even in the
intensive care unit so this is a list that the EPA is put together of
registered antimicrobial products for use against coronavirus SARS cub - the
cause of kovin 19 this is what we've been waiting for it was put out on March
3rd we'll put the link to this in the description below so you can see that
bleach and peroxide and certain chemicals here are to you by the way is
ready to use and dilute a bowl something that you can dilute but you can see here
there's a number of products that are certified to clean and disinfect
surfaces that are colonized by the SARS cub to virus so I want to talk about
this interesting research article the research was done by experts at Peking
University in Beijing Shanghai University and the Chinese Academy of
Sciences the gist of the article is we have the SARS cuff - virus and what
they're saying is that there's two types there is an ancestral s type which was
starting before at the very beginning of the outbreak and there's been a mutation
that's branched off the original is known as the S form and the mutated form
is known as the L form how they differ is at a single point where there's been
a mutation of one nucleotide that's known as an SNP a single nucleotide
polymorphism so for instance in the genome instead of having an a G T which
would be in the S type the mutated L version the one that's branched off is
gonna be a G C at that point there's been a change of a nucleotide and that's
caused a difference this L and s form the S being less severe but the more
original form was seen only 30% of the time in wuhan the more severe one ended
people up in the hospital and they were quarantine that's been reduced and it's
been decreasing whereas the 30% one is the one that seems to be spreading and
so let's take a look at some of their data in that article and here is the
article itself we'll put a link in the description below and here's a Fulani
tree where you can see that the red arrow is the S and the blue arrow the L
there's also further analysis again the red dots being the S version and the
blue dots being the descendants or the more severe one here you can see the - L
and s types and you can see that there is a transition there where the S type
seems to be more similar to the other coronaviruses with a T at this position
in this gene changed to a C and that became more variant in the L type which
is the blue one and you can also see it where this went for instance you can see
here there's a strain that went to France
Germany there's some that have gone to South Korea the United States the United
States Singapore Japan but also some of the s-type has also gone to the United
States to Australia to Korea Japan etc etc in terms of the number of strains
looking at this first part of the graph outside of Wuhan there was a lot more of
the s-type whereas inside Wuhan there was a much much higher concentration of
the newer l-type which was also more severe looking at the second part of the
graph before January 7 versus after January 7 the s-type was making much
more of a comeback unfortunately you can't really choose what form of the
virus you get infected with and according to the authors of the study
you may actually get both apparently the virus is identified from a patient in
Australia had multiple degenerated nucleotides and the best explanation is
that this patient was infected by at least two different strains of SARS
curve two viruses and you can see here that looking at the two nucleotides at
these positions they were different even though this was in the same person of
course the other possibility is that the patient may have had mutated viruses in
them at the same time which is unlikely the authors and their abstract saying
that these findings strongly support an urgent need for further immediate
comprehensive studies that combine genomic data epidemiological data and
chart records of the clinical symptoms of patients with coronavirus disease
2019 thanks for joining us