In the 1950s David and Alice Schwartz were on their way to establishing
Bio-Rad as a leader in life science research.
Since then Bio-Rad has continually introduced innovative products that stay
true to our commitment to quality,
reliability,
productivity,
and ease of use. Bio-Rad recognized that bead-based multiplex technology
was the next step forward in immunoassays.
Now laboratories around the world trust Bio-Plex instruments, assays, and
software to deliver precise results in less time with less work and lower sample
volumes.
Bio-Rad provides instruments to meet the needs of researchers in different
environments: the versatile Bio-Plex 200 suspension array system
and the high-throughput Bio-Plex 3D system.
Bio-Plex multiplex technology backed by Bio-Rad's world-class service and
support delivers increased productivity and consistent results. Bio-Plex
multiplex technology uses bead-based assays that are all carried out in a
single reaction well.
Each bead is colored with a unique mix of red and infrared fluorphores for
identification and specific antibodies are coupled directly to the surface of each bead.
The coupled beads are combined within a single well of a plate to measure multiple
analytes from one sample.
Biotinylated detection antibodies are added to quantify analytes, allowing
instruments to measure fluorescence of biotin-bound streptavidin
phycoerythrin conjugates.
Lasers read the color code of each bead and its bound analytes, providing quantitative data on
multiple biomolecules from one sample.
This is the power of multiplexing.
Bio-Plex assays measure important biomarkers implicated in inflammation,
autoimmune disorders,
cancer,
diabetes,
and intracellular signal transduction.
Protocol setup is effortless with Bio-Plex Manager software.
Get results faster,
analyze your data with confidence, and easily customize data presentation to
suit your needs.
The Bio-Plex systems are highly automated, making them easy to operate and produce
reliable results.
And all Bio-Plex systems, assays, and software are built on Bio-Rad's commitment
to delivering reliable technology that improves your research experience.
A commitment that Bio-Rad has maintained for decades.
The very important thing is
if we are going to be doing research
in childhood
heart disease,
now we're going to be doing
blood sampling,
and you obviously have to be very, very aware that there's just so much blood that these young
babies have. We went from 100 µl of plasma for one analyte
down to 10 µl of plasma that would allow us to measure over 22 different analytes.
So this system — because of the fact
that it allows
multiple measurements on the same sample —
really affords us the first time
to do something they've never been able to do before,
which is to serially measure
changes in inflammatory cascades, not just at one point
but at multiple times points in the course
of heart disease, in the course following heart surgery,
and really put a time map
on how things change in
the operating room,
in the intensive care unit, and beyond.