In this video I’m going to share with you my own personal Bremelanotide experience,
also known as PT 141. Touted as the latest and greatest cure for erectile dysfunction,
we’ll take a close look to see just how effective it is.
So stay tuned for my PT-141 review.
Hi, I’m Lance Hitchings and if you enjoy this type of content, then please subscribe
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Today, we’re gonna take a look at Bremelanotide…PT141.
One of the best drugs for erectile dysfunction that I’ll bet you’ve never heard of.
I’ll be explaining just what it is, and a little of its history.
I’ll tell ya where to get it, and how to take it.
I’ll cover the effects of PT 141, and then I’ll discuss with you my own personal experience with taking Bremelanotide.
OK, a little bit of science.
Bremelanotide is a cyclic heptapeptide lactam analog of alpha-melanocyte-sitmulating hormone, or MSH.
That’s quite a mouthful, but what you should take away from this
is that it’s a peptide, which is a short-chain amino acid, and that
and that it’s very similar to a group of peptide hormones that stimulate a type of cell in our skin,
called a melanocyte, to produce melanin, the pigment that makes us look tan.
But melanocyte-stimulating hormones also has a bunch of other functions.
MSH can also suppress appetite, it has anti-inflammatory effects,
it can influence the release of aldosterone, which regulates the salt and water balance in out bodies…
and it has an impact on sexual behavior, and that’s the effect that we’re looking for here.
Now, I need to give you guys some definitions here.
The word agonist refers to a chemical that binds to a receptor, that activates a receptor.
Antagonist refers to a chemical that blocks the action of an agonist.
And inverse agonist is a chemical that causes an action that is the opposite of the agonist.
So, Bremelanotide is a non-selective agonist of the melanocortin receptors,
otherwise known as MC receptors,
primarily acting as an MC3 and MC4 receptor agonist.
MC4 acts as a regulator, among other things, for sexual behavior and male erectile function.
So, Bremelanotide activates the melanocortin 4 receptor, impacting sexual behavior.
In the early 1960s, research showed that administration of α-MSH in rats caused sexual arousal,
and this research continued up through the 1980s.
Then, scientists at the University of Arizona began attempting to develop α-MSH,
along with analogs, as a potential sunless tanning agent.
And they developed several analogs, including Melanotan-I and Melanotan-II.
One of the scientists, Mac Hadley,
injected himself with twice the dose of Melanotan-II that he intended
and experienced an 8-hour erection...as a result.
To pursue the potential sexual dysfunction agent,
Melanotan-II was licensed to a company
who then stopped development of Melanotan-II and started development of bremelanotide.
Bremelanotide is thought to be a likely metabolite of Melanotan-II.
This company, Palatin Technologies, developed an intranasal delivery system
and began Phase II trials for both female sexual dysfunction and male erectile dysfunction,
but the FDA halted these trials due to an increase in blood pressure
among a small segment of the clinical trial subjects.
The drug was then reformulated to be delivered by injection, and trials continued,
with Phase III trials and a New Drug Application filed with the FDA in June, 2018.
I’ve heard that the new drug might be sold under the trade name of either Vyleesi or Rekynda.
Now, rumor has it that at one point in it’s development,
after a possible ban by the FDA or after the FDA halted testing,
the staff of doctors and scientists who had developed bremelanotide put it all out on the internet…
everything, the test results and the formulation and sequencing information.
So that anyone could formulate it.
All I know is that if you do a search for bremelanotide to buy on the internet,
you’ll find countless companies that formulate it and sell it on the internet.
So, what does it do. To answer that, let’s take a look at the big 3 erectile dysfunction medications:
Viagra, Levitra and Cialis. They are all phosphodiesterase 5 blockers, or PDE5.
PDE5 is an enzyme that promotes the breakdown of cyclic-GMP,
which is a chemical compound that relaxes the smooth muscles in the walls of the arteries of the erectile tissue,
allowing blood to rush in and causing an erection.PDE5 breaks down cyclic-GMP,
allowing the blood to drain from the penis and causing detumescence.
So the big 3 ED medications work directly on the erectile tissue of the penis.
Bremelanotide works differently. Instead of working on your plumbing, bremelanotide works on your libido,
your sex drive…your overall desire for sexual activity. In other words, it makes you horny as hell.
And it lasts for anywhere from 24 to 48 hours. But more about that later.
Now, as I mentioned, PT-141 is currently under development by Palatin Technologies,
and is not currently available for purchase, with or without a prescription, in the United States.
But it’s available pretty much everywhere outside of the United States.
Like I said earlier, if you do a search for where to buy Bremelanotide on the internet,
you’ll find countless companies willing to sell and ship you the product.
And China seems to lead the field.
I’ve found that a trading company called Alibaba will sell just about anything made in China,
and this includes consumer electronics, apparel, vehicles…and chemicals.
You can buy it in any quantity from a single, 10mg vial to as many boxes of 10 vials as you want to buy.
Pricing ranges from $25 - $40 for a single vial, to about $100 for a box of 10 vials,
to about $50 a box if you buy more than 10 boxes.
Which means that you can purchase a single dose for as little as 50 cents for a 10mg dose.
On a side note, you can also get sildenafil, vardenafil, and tadalafil,
which are the generic names for Viagra, Levitra and Cialis, respectively,
in powdered form, for about a $1 - $10 a gram, depending on the quantity you buy.
So if you purchase 100 grams of tadalafil, at $1 a gram,
that’ll run you about $100. That’s 5,000 20mg doses. That's about 50 cents per dose.
Now, if you compare that to the retail price of Cialis in the US, that's about $30 a dose. Just saying.
So what do you think…does this sound like something that you might like to try.
Leave me a comment below and let me know if you've ever heard of Bremelanotide,
and what you think about it.
OK, now we come to the tricky part, because the best way to take bremelanotide,
to get the best results, is to inject it. Now, I’m not talking about shooting up as if it were heroin or something.
I’m talking about injecting it as if it were insulin, in the stomach.
So here’s what you do. Bremelanotide comes in a vial with 10mg of freeze-dried powder in it.
Now, you’ll need some bacteriostatic water, which you can find on the internet, to rehydrate it.
Bacteriostatic water is sterile water with 0.9% benzyl alcohol added
to prevent the growth of any bacteria as a result of multiple entries into the container,
usually with a sterile needle.
You’ll also need some syringes…I use 1/2”, 30 gauge insulin needle that holds 1mL.
That’s the equivalent of 1cc. You’ll also need some alcohol wipes.
First, after opening the aluminum seals on the top of the bacteriostatic water and the vial of bremelanotide,
you’ll want to sterilize them by wiping them down with the alcohol wipes.
Then, inserting a syringe into the vial of bacteriostatic water, draw off 1 ml, or 1 cc.
Insert this syringe into the rubber on the top of the vial of bremelanotide,
aiming the needle at the side of the glass. Slowly, inject the water into the vial,
letting it run down the side of the glass and come into contact with the powder.
Slowly rotate the vial, until all of the powder is dissolved.
This won’t take long, with most of the powder dissolving instantly,
but some of the powder may take up to a minute or two to fully dissolve.
Now, this is important, because the powdered bremelanotide is fragile and you don’t want to agitate it.
You could break down the peptide, breaking the chain of amino acids, and then it would be useless.
Now, take another alcohol wipe and wipe down the area of skin that you’re going to inject into.
This should be about 3 inches to either side of your belly button.
Then take a second syringe, stick it into the vial, turn the whole thing upside-down
and draw off the amount that you want to inject. This is generally 0.1 ml, or 10 units, to 0.4 ml, or 40 units.
I would start with 0.1 ml and gradually work your way up to whatever amount works for you.
For me, it was 0.3 ml. But you’ll need to experiment to find out what your own PT 141 dosage is.
Now, what I do is I draw off slightly more than I intend to inject, then I hold the syringe with the needle up,
and I flick the syringe with my finger a few times to release all the air bubbles,
and then I push in the plunger to expel all of the air and some of the liquid
until the plunger is at the exact amount I want to inject.
But honestly, when your injecting into the skin like this,
air bubbles aren’t really a concern.
They’re a danger only if injecting directly into a vein.
Now, for me, this is pretty easy, since I spent a year self-injecting interferon to cure hep-C.
But the first time I did that, I spent the better part of an hour,
trying to work up my courage to stick myself with the needle.
And it was mostly because I didn’t know how hard to poke myself to get the needle to go in.
Let me tell you, these needles are sharp, and they’ll go in without you even being able to feel it…most of the time.
What I do is I don’t start an inch or two away and jab at myself…
I touch my skin with the tip of the needle and then just slide it in. Works great.
So, I’ve been doing bremelanotide for a few months now, and I can report on my experience with the drug.
I’d like to describe the PT 141 side-effects first. As soon as I inject it, almost instantly,
I get a feeling of slight nausea. Nothing that I can’t ignore.
This appears to be a common side-effect. I’ve followed a forum of gents doing bremelanotide,
and a lot of them report this same side-effect.
One of them said that he treated the nausea successfully with a Tums, or Rolaids,
but I haven’t tried that…mostly because it’s just not that severe.
I also noticed that if I injected bremelanotide frequently, like every other day,
the feelings of nausea upon injection went away.
I also noticed that when I did it every other day, it also became more effective.
I’ve only done it every other day for about 3 weeks, and I did the same amount every time.
I feel now like once it becomes more effective and no longer causes nausea,
I might be able to get the same effect with less.
Also, when I first did it, it took about 8 hours to kink in…
after I’d been doing it for a while, it only took 2-4 hours to kick in.
So I feel like, if I've been doing it for a while, live every other day, my body tolerates it better,
and it's more effective
So, I started out doing 0.1ml, and that had no noticeable effect.
I then upped it to 0.2ml, and that’s when I noticed an effect…although it was slight.
So then I upped it to 0.4ml…and that’s when the full effects kicked in. Now, I do about 0.3ml.
OK, so this first part is a little difficult for me, because I'm a private person.
And talking about my sexual experiences is not that easy for me.
So, first off, I was incredibly horny, and that lasted for a couple of days.
Now, that's not something that I ever experienced before with any of the big 3 ED medications.
Let’s just leave it at that.
I also had a woody that just wouldn’t quit. I had done it in the morning the first time,
and it kicked in about 8 hours later. And I had an erection all night long.
In fact, I was worried about priapism, which is a persistent erection lasting longer than 2 hours,
and which can be dangerous…and harmful to your penis.
But apparently that’s for a rock-hard erection…
and the erection that I got from bremelanotide didn’t quite make it to “rock-hard” status.
And for all I knew, it might have occasionally gone done while I was asleep.
At any rate, no harm, no foul.
Even though I had an erection most of the night, I suffered no ill effects.
But the next day, it was still fully in “activated” mode, and my erection persisted on and off for most of the day.
Now, this didn’t really bother me at all,
but I could see if I was in a working environment, it might be a problem.
Now, one thing I did notice. My erections seemed to be fuller at night when I was asleep
than they were during the day, and during those periods when I wanted to have sex.
And this seems to be another common effect, with several of the men on the forum reporting a similar experience.
However, I took an ED med, and that seemed to resolve that…
even though I’m a guy who doesn’t experience great results from ED meds.
In this case, it worked just fine.
OK, so…there you have it. We’ve gone over a bit of the science and history of Bremelanotide,
we’ve talked about effects, where to get it and how to take it.
And I’ve shared with you my personal experience with taking Bremelanotide.
And I guess the bottom line is this…
would I recommend this for other guys your have ED, if they could have the same experience that I did?
Well, no. I'm not a physician, so I don't feel that I can go out on a limb and recommend this product for anybody.
I can only report on my own experience. And I loved it, I thought it was great.
It made me feel like a teenager again. The only downside that I can think of,
was that I had an erection at times that I didn’t really want one,
but it’s been so long since that was a problem for me, that I almost welcomed it.
OK, so that wraps up this video.
Leave me a comment below and let me know how likely it is that you’re going to try Bremelanotide for yourself.
And if you have tried it, how did it work for you?
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Hit the Like button. Thanks for watching. I’m outta here.