ivermectin is an fda-approved medication for parasitic infections ivermectin is widely
available due to its inclusion on the w-h-o model list of essential medicines it opens glutamate
sensitive chloride channel currents in helmets and it's widely believed that this is how it
kills certain parasites it's the drug of choice for the treatment of unko sir Caius and stronzo
Lord Isis both of which are parasitic infections ivermectin is effective against several intestinal
nematodes including ascariasis try crisis and also cutaneous larva migrans also Lucci Rhea
Bancroft II Bru gia Malaya Manson Ella oz Rd and lo Aloha it also is effective against scabies and
head lice so why my ivermectin work against SARS coronavirus - the virus that causes covid 19
well once the virus gains entry into the cells of the body using the h2 receptor the virus releases
its messenger RNA into the cell the cell starts to translate the messenger RNA from the virus which
starts to make of viral proteins and that's how new virus forms but some of these viral proteins
that are freshly made then enter into the nucleus of the cell or at least are thought to do so by
many scientists and this probably impairs our cell's ability to fight off the infection the
way these viral proteins are thought to gain entry into the nucleus of our cells is through specific
channels that are made out of a different protein called important not important it's important
there's important type alpha and type beta or imp alpha and Impa beta for short and this is
where ivermectin comes in because ivermectin inhibits the passage of these viral proteins
into the nucleus it does so by binding to these protein channels and effectively blocking the
transport of molecules through them so this is why scientists started studying ivermectin and
here we have this article that just came out April 3rd in the journal antiviral research
this is a pre proof article meaning they've been peer-reviewed but final publication is
still pending what these scientists found is that ivermectin significantly inhibits the SARS
to coronavirus viral proteins in their passage from the cytoplasm into the nucleus of the cells
in vitro in vitro means this was done in a test tube or outside of a living organism so a single
dose of ivermectin had a 5000 fold reduction in virus levels at 40 hours in cell culture so
this drug has a huge impact on this virus in vitro and that's why the authors of the study
conclude that these drugs need to be studied in covid 19 patients meaning in clinical trials the
same way that other drugs are being looked at in clinical trials for Covid 19 such as REM des aveer
chloroquine and hydroxychloroquine so because ivermectin is generally considered a safe drug
and is already fda-approved for other diseases it can be repurposed for covid 19 as long as
it's shown to be safe and effective for covid 19 in patients in these clinical trials now if this
drug turns out to be the miracle drug for Covid 19 the next question will become when should it be
started in other words at what point to someone started taking this medication should they take
it prophylactically or should they take it as soon as they start getting symptoms but we're
not even at that point yet first we have to do the clinical trials to see if it is effective for Covid 19
the other question is what are the side effects of ivermectin or adverse reactions well based on
what we already know about ivermectin this is what I can tell you the most common adverse
reaction is the Masotti reaction but this only happens when ivermectin is used to treat an cosec
Isis which is a parasitic infection now what is the Masotti reaction you ask it was first
described in 1948 it's a symptom complex seen in patients after undergoing treatment of nematode
infestation particularly with the medication diethyl carbonate or Dec for short but it also
occurs with ivermectin lazatti reactions can be life-threatening and are characterized by fever
hives generalized swelling swollen lymph nodes fast heart rate low blood pressure joint pain
and abdominal pain there's a 25% chance of Masotti reaction when ivermectin is used to treat on
qussuk Isis but not other parasitic infections so for covid 19 patient took ivermectin this
would not happen so otherwise every mechanism side effects are uncommon diarrhea occurs in about 2%
of people taking it also ivermectin should not be ministered to pregnant or lactating
women in the safety and children who weigh less than 15 kilograms is still not known