When you have Parkinson's you have a lot of different things taken away from you. One important one was walking
I always liked walking
My Parkinson's was bad enough that I could not respond quickly to changes in the environment
It was hard for me to get started, and you'd freeze when you tried to make a corner and I'd just get stuck
And I remember thinking when I first had Parkinson's, how do you get stuck. How do you not be able to walk?
But sure enough, that's exactly what happens. You get stuck. You just can't initiate movement
Steve Gilbert is a Seattle scientist,
researcher, and educator who has studied how toxins damage the brain for his entire academic career. In
2005 he was diagnosed with a brain disorder of his own,
Parkinson's disease
He'd noticed a tremor in his right foot for a few years before his formal diagnosis
Once he was diagnosed he tried taking some of the medications that are often prescribed, but he didn't like the side effects
Something had to be done because I was not taking any drugs
My symptoms were getting worse. I was becoming increasingly debilitated. I couldn't travel by myself anymore
And I couldn't drive. The pleasures of life were just being gradually taken away
With DBS I procrastinated because
the side effects are
stroke,
potentially, or brain infection. And
For me, as a scientist, they couldn't tell me how it worked
Despite the risks Steve eventually agreed to have a surgical procedure
called deep brain stimulation
The surgeon would put two wires in his brain called leads. About a week after that
Steve's surgeon put a pacemaker device near his collarbone that would direct the two wires to send out
electrical impulses. These impulses, carefully targeted to his brains motor control center, were intended to
interrupt Steve's tremors. Steve had to wait a month to find out if the treatment had worked
You go through all this to have brain surgery, and it's fairly invasive stuff, and
then they implant the
generator and they make you wait. You wait, wait wait
So I had all these people in the room, waiting to see. And they turned it on. And it worked
great. And I could get up out of the chair. Because getting up, standing up is really difficult. You are trying to get your balance straightened out
So I could get up out of the chair, I could walk down the hall and back. It was incredible.
Parkinson's disease damages a part of the brain that makes a chemical called dopamine
It is the absence of dopamine that leads to the involuntary movements known as tremors
But why electrical stimulation quells the tremors is not entirely understood
Steve has a device that allows him to change the impulse sent to the leads in his brain. Making the impulses stronger or weaker
can change the tremor
Steve is one of a minority of patients who are eligible for deep brain stimulation
It's not right for everyone. But he's part of a huge group--an estimated 60,000 people--
diagnosed every year in the U.S. He thinks DBS could help more people and help them earlier
There's a lot to know about deep brain stimulation
But one of the things to know is it can be phenomenally good
Feeling that I could walk around
and the tremor was gone. It was just unbelievable