>> It's hard to describe how much it affects your life,
not being able to leave the confines of your house.
Okay, so this is a 2002 Thunderbird that I restored.
They only made 60,000 of them.
This is the car that I go on all my road trips with.
And three years ago, I had to stop doing that,
four years ago, because the symptoms, the cancer symptoms,
made it impossible to do it.
>> Hi, Mr. Charnley. >> Nice to see you.
>> Nice to see you.
>> Hello, Jeff. >> How's it going?
>> How are you?
>> When we met Bob, he was essentially home bound,
had stopped traveling, stopped seeing friends.
He had really given up all the things
that he cared for or was interested in.
>> The carcinoid syndrome has a bunch of different symptoms.
But mine, you have diarrhea, constant diarrhea.
So I couldn't do anything.
I was pretty much...
I was stuck, and I was a prisoner at my home.
I just stayed there, didn't go anywhere.
So I've had two liver resections down in Winchester,
and they've taken four or five tumors off the liver.
Then they were gonna do another liver resection.
I said, "I've had three operations now."
I said, "I don't want to do this again."
And I started doing some research.
I found the department in Hopkins.
So I called up and said,
"I want a second opinion on this surgery."
And I went up and I saw Dr. Heat.
He said, "Well, we don't think surgery is appropriate here.
"We've got something we think is better for you."
>> Theranostics is a new way to manage cancer.
It's a new way to treat cancer
whereby we find a very specific molecular target,
and then we first image the patient
in order to determine whether they have the target.
And if they do have that target,
then we will come in and use a molecular radio therapeutic
that hits the same exact target as the imaging agent did.
Once the specific target is identified,
the therapeutic agent is injected intravenously
into the forearm.
Then it navigates the bloodstream
and finds the exact location on the tumor.
The therapeutic agent is then internalized
in the malignant cell,
where it's able to deliver a localized dose of radiation
directly to the effected cell
rather than more broadly treating the disease
and the location in which it presents.
>> With the first treatment,
about a month after the first treatment,
things got dramatically better.
And maybe two months, I was out having dinner
with my son and his wife again.
It doesn't sound like a whole lot,
but when you can't do it, (laughs)
going to a restaurant's a pretty big deal.
>> So Bob has done really well.
We see him every six months.
We do a scan with the diagnostic agent
to see what his tumors look like.
But given the remarkable response he's had so far,
we expect that he'll do well.
>> Well, the reason why we think
theranostics is a game changer
is the tremendous benefit to the patients
in terms of their quality of life.
Radiology is normally thought of
as a set of imaging modalities.
But more recently, we're doing
more advanced functional techniques.
So radiology is increasingly becoming
in itself a therapeutic modality.
>> Four years ago, before it got bad,
I'd take road trips across country a couple of times
in just about every state.
So Dr. Solnes came in, and we were talking,
and I told her, I said, "I love to take these road trips.
"And I hadn't been able to take one."
And I told her about the Grand Canyon and all that stuff.
And she said, "Well, hopefully you'll be able
"to do that now.
"And if you go, you better send us pictures."
And the luminotherapy was the last hope for that.
And luckily it worked.
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