good evening
we are
starting new presentations or cycle
presentations targeting
specifically products
which were designed for gluten-free
remedies
and today we'll talk about one of the
latest additions to
the list of our supplements which is
arjun and a guava leaf extract
most of our supplements design on the
basis of the
needs in our clinic and this particular
supplement is not an exception
specifically it is designed
to work for
patients who have
chronic
yersinia infection or so-called
yersiniosis and for those who have
resistant
gastroenteritis or resistant infection
with helicobacter pylori
so let's start with guava leaves
so guava is a tropical fruit which
also
grows in california and also not too
many people know that it is a medicinal
plant which is mainly distributed at
tropical and subtropical areas
the leaves of the guava plant have been
studied for their health benefits
and
they contain quite a few
phytochemicals such as quercetin
avicularin apigenin and so on and so on so
i listed some of the chemicals or some
of the
natural products extracted from guava
plant leaves in here for your curiosity
so uh biological activities of guava
leaf extract are quite broad
and
they've been shown to inhibit
cancer growth specifically colon and
breast cancer
guava leaf extract has anti-diabetic
activity and it lowers glucose level in
the blood
it has obviously antioxidant activity
uh a lot of people from south america
using guava leaf extract to treat
chronic diarrhea
so guava leaf extract also protects
liver and we called hepatic protective
activity
it has mild
lipid lowering or cholesterol lowering
activity and lowers both triglycerides
and ldl
so it can be used as an adjunct therapy
for weight reduction
and not too many people know but guava
leaf extract also suppresses cough and
can be used as adjunct therapy to treat
bronchitis
so guava leaf extract also
is known to have a pretty strong
anti-microbial activity
so a number of publications show that
guava leaf extract inhibits growth of
both gram-positive and
gram-negative bacteria such as
staphylococcus streptococcus pseudomonas
and specifically yersinia enterocolitica
and yersinia pseudotuberculosis it also
inhibits the growth of salmonella
bacillus ceres proteus and shigella
as well as pathogenic e coli
again uh in our clinic we're using
specifically to treat uh
yersinia infection chronic yersinia
infection due to yersinia enterocolitica
and yersinia pseudo tuberculosis
so specific ingredient specific
flavonoids isolated from a guava leaf
extract
been shown to have
activity against
microorganisms and i listed them in the
second paragraph
and
it also been shown that not only is guava
leaf extract an anti-microbial but
it also can affect
specific immune pathways and up
regulates production of
il-7
which benefits patients with various
inflammatory conditions and specifically
inflammation within the gastrointestinal
tract
so i decided to quote a couple of
articles so this particular article
talks about guava leaf extract as a
gastroprotective
remedy and a remedy which inhibits
helicobacter pylori growth
so
let's talk about the second ingredient
in our product which is arjun
so terminalia arjuna is a plant which
has been traditionally used
in ayurvedic
medicine for a number of years probably
several hundred years
in india is commonly known as arjuna or
arjun
so arjun's bark is considered to be the
most important constituent from medical
standpoint although leaves can be also
used
and again i listed
chemicals which are major constituents
of
arjun bark
so traditional use of arjun in india
includes treatment of angina factories
or coronary artery disease so treatment
of chf or congestive heart failure
treatment of various cardiomyopathy post
myocardial infarction hypertension
hyperlipidemia and diabetes as you can
see the mainstream indication for arjun
is various coronary artery disease and
various vascular diseases however
however
arjun also has pretty strong
antimicrobial activity specifically
against
negative microorganisms
so it also reduces uh gastric
inflammation
it also has
inflammatory activity
and uh
inhibits quite a few uh pro-inflammatory
cytokines and it has pretty strong
antioxidant activity
after doing numerous research we decided
to combine our highly concentrated
guava leaf extract and highly
concentrated
arjun bark extract to create
one remedy containing both
so again the main indications for the
use of guava leaf arjun extract are
gastrointestinal infections such as
yersiniosis
irritable bowel syndrome with
predominant diarrhea
mild form of colitis where it can be
used as an adjunct therapy as well as
gastritis and peptic ulcer disease due
to h pylori we would not recommend to
use it as a sole therapy of h pylori
but in conjunction with antibiotics or
other antimicrobial herbs it presents a
quite powerful tool to treat h pylori
infection
so in addition
we design also a tincture which we call
yersin which also contains a
corn alcohol-based extract of guava leaf
and arjun bark and also it contains
small amount of neem extract
so i studied quite a few
pharmacokinetic
data on
both arjun and guava leaf extract and
based on my studies i came to the
conclusion that it makes perfect sense
to use both tinctures and solid extract
together to increase their potency
so that's why we have two different
products
one liquid one solid with very similar
composition
so again as i mentioned before uh we
designed guava leaf
and arjun extract specifically to target
yersiniosis
we do see quite a few patients with
yersiniosis in our practice and i
think that it's a highly highly
unrecognized infectious disease chronic
infection
so it's a chronic infection which is
caused by yersinia enterocolitica and to
a lesser degree
by
ursinia pseudo tuberculosis
and manifesting in the form of chronic
right-sided abdominal pain
low-grade colitis low back pain
primarily on the right side
as well as various forms of arthritis
more frequently it's arthritis of the
right hip
the therapy of yersiniosis is based on
long-term use of anti-inflammatory drugs
and antibiotics and that's why we've
been looking for
natural adjunct therapy to speed up the
recovery of these patients
we
found that guava leaf and arjun is a
promising botanical supplement in a
complex therapy of yersiniosis
so
this slide shows typical drug
nutraceutical combination in the therapy
of yersiniosis
which we are using in our practice
so for example you can use sulfasalazine
plus guava leaf slash arjun
extract both solid and tincture and we
also like to use bacillus coagulans
which is very strong anti-inflammatory
probiotic
you can use a different combination or
slightly different combination including
sulfasalazine doxycycline guava leaf plus
arjun
solid extract and tincture plus leaky
gut probiotic which is another brand
probiotic use as a part of gluten-free
remedies uh you can use
another protocol for those patients
who are sulfur sensitive which is five
amino salicylic acid guava leaf plus
arjun and bacillus coagulants or five ac
doxycycline guava leaf and arjun and
leaky gut probiotic all these things
been used in our practice for a while
and we're very satisfied with outcomes
and here i decided to show a couple of
articles about using guava leaf extract
in the therapy of gram-negative
anthropogenic bacteria and yersinia in
particular so this particular article
talks about that after exposure to guava
leaf extract yersinia stop secreting
outer proteins and
basically
become much much less pathogenic
so
and again this japanese group of
authors suggested that after exposure
to guava leaf extract uh
yersin became not very pathogenic and uh
the conclusion was that guava leaf
extract can be used successfully as a
part of adjunct therapy uh in patients
with yersiniosis
so another article talking about
arjuna as anti yersinia
natural remedy and apparently
concentrated extract of arjuna
is comparable to tetracycline in terms
of its antimicrobial activity which is
quite
amazing so
again this article talks about using
arjun extract in therapy of mild
colitis
and again
it's been described as an inhibitor of
cytokines
involved in progression of
ulcerative colitis
so quite a few patients in our
practice also using a pure
neutraceutical protocols
honestly speaking we prefer to start
with
drugs plus
botanicals and then after
yersinia is under control switch them
to botanical protocols but always there
are some exceptions so this is the
protocol which can be used in the treatment
of yersiniosis it includes guava leaf plus
arjun
both solid and tincture berberine extract
bromelain
ashoka neem manjistha plus anantamul
very powerful prebiotic which is
mannan oligosaccharides
and two probiotics bacillus coagulans
and leaky gut probiotic
for h pylori we're using slightly
different combination which is again
guava leaf extract plus arjun
DGL licorice plus mastic gum
helicop which is another part of our
gluten free remedies arsenal and we'll
talk about that in one of the
presentations
and N-acetylcysteine which is
specifically used as a biofilm breaker
for h pylori berberine
olive leaf tincture and bovine
immunoglobulins we're also using uh our
own product which is a combination of
lactobacillus reuteri and saccharomyces
boulardii which specifically was
designed to treat h pylori and c diff
so uh what are the typical doses which
we recommend
for the guava leaf and arjun extract
we recommend typically two capsules
twice a day
for those who are very sensitive they
can start with one capsule a day and
then go up we don't recommend to go
above
four capsules a day because this product
can cause constipation
the recommended dose of yersin tincture is
30 drops per glass of water twice a day
and what are the contraindications
so typically it's ongoing anti
coagulation therapy
allergy to guava fruit and pregnancy
these are very standard
contraindications
honestly speaking we don't see too many
problems with
side effects when we use this particular
product in our population of patients
thanks
if you have any questions please
contact us through gluten-free remedies