- [Instructor] A company screens job applicants
for illegal drug use at a certain stage
in their hiring process.
The specific test they use has a false positive rate
of two percent and a false negative rate of one percent.
Suppose that five percent of all their applicants
are actually using illegal drugs
and we randomly select an applicant.
Giving the applicant test positive,
what is the probability that they are actually on drugs?
So let's work through this together.
So first let's make sure we understand
what they're telling us.
So there is this drug test for the job applicants
and then the test has a false positive rate of two percent.
What does that mean?
That means that in two percent of the cases,
when it should have read negative,
that the person didn't do the drugs,
it actually read positive.
It is a false positive.
It should have read negative but it read positive.
Another way to think about it.
If someone did not do drugs and you take this test,
there's a two percent chance
saying that you did do the illegal drugs.
They also say that there is a false negative rate
of one percent.
What does that mean?
That means that one percent of the time
if someone did actually take the illegal drugs,
it'll say that they didn't.
It is falsely giving a negative result
when it should have given a positive one.
And then they say that five percent of all their applicants
are actually using illegal drugs.
So there is several ways that we can think about it.
One of the easiest way to conceptualize is just,
let's just make up a large number of applicants,
and I'll use a number where it's fairly straightforward
to do the mathematics.
So let's say that we start of with 10,000 applicants.
I will both talk in absolute numbers,
and I just made this number up.
It could have been 1,000, it could have been 100,000,
but I like this number 'cause it's easy to do the math
better than saying 9,785.
This is also going to be 100% of the applicants.
Now they give us some crucial information here.
They tell us that five percent of all their applicants
are actually using illegal drugs.
So we can immediately break this 10,000 group
into the ones that are doing the drugs
and the ones that are not.
So five percent are actually on the drugs,
95% are not on the drugs.
So what's five percent of 10,000?
So that would be 500.
So 500 on drugs, on drugs.
Once again, this is five percent of our original population.
And then how many are not on drugs?
Well 9,500 not on drugs.
And once again, this is 95% of our group of applicants.
So now let's administer the test.
So what is going to happen when we administer
the test to the people who are on drugs?
Well the test, ideally, would give a positive result.
It would say positive for all of them,
but we know that it's not a perfect test.
It's going to give negative for some of them.
It will falsely give a negative result for some of them,
and we know that because it has a false negative rate
of one percent.
Of these 500, 99% is going to get the correct result
in that they're going to test positive.
So what is 99% of 500?
Well let's see, that would be 495.
495 are going to test positive.
I will just use a positive right over there.
And then we're going to have one percent,
which is five, are going to test negative.
They are going to falsely test negative.
This is the false negative rate.
If we say, what percent of our original applicant pool
is on drugs and tests positive,
well 495 over 10,000.
This is 4.95%.
What percent is of the original applicant pool
that is on drugs but tests negative for drugs?
The test says that hey they're not doing drugs.
Well this is gonna be five out of 10,000.
Which is 0.05%.
Another way that you could get these percentages.
If you take five percent and multiply by one percent,
you're goin to get 0.05%.
500ths of a percent.
If you take five percent and multiply by 99%,
you're going to get 4.95%.
Now let's keep going.
Now let's go to the folks who aren't taking the drugs.
And this is where the false positive rate
is going to come into effect.
So we have a false positive rate of two percent.
So two percent are going to test positive.
What's two percent of 9,500?
It's 190 would test positive
even though they're not on drugs.
This is the false positive rate.
So they are testing positive,
and then the other 98% will correctly come out negative.
The other 98%, so 9,500 minus 190,
that's gonna be 9,310 will correctly test negative.
Now what percent of the original applicant pool is this?
Well 190 is 1.9%,
and we could calculate it by 190 over 10,000
or you could just say two percent of 95% is 1.9%.
Once again, multiply the path along the tree.
What percent is 9.310?
Well that is going to be 93.10%.
You could say this is 9,310 over 10,000
or you can multiply by the path
on our probability tree here.
95% times 98% gets us to 93.10%.
But now I think we are ready to answer the question.
Given that the applicant tests positive,
what is the probability that they are actually on drugs?
So let's look at the first part.
Given the applicant tests positive.
So which applicants actually tested positive?
You have these 495 here tested positive,
correctly tested positive,
and then you have these 190 right over here
incorrectly tested positive,
but they did test positive.
So how many tested positive?
Well we have 495 plus 190 tested positive.
That's the total number that tested positive,
and then which of them were actually on the drugs?
Well of the ones that tested positive,
495 were actually on the drugs.
We have 495 divided by
495 plus 190
is equal to 0.7226.
So we could say approximately 72%.
Approximately 72%.
Now this is really interesting.
Given the applicant tests positive,
what is the probability that they are actually on drugs?
When you look at these false positive
and false negative rates, they seem quite low,
but now when you actually did the calculation,
the probability that someone's actually on drugs is,
it's high, but it's not that high.
It's not like if someone were to test positive
that you'd say oh they are definitely taking the drugs.
And you could also get to this result
just by using the percentages.
For example, you could think in terms of
what percentage of the original applicants
end up testing positive?
Well that's 4.95% plus 1.9%.
4.95, we'll just do it in terms of percent, plus 1.9%,
and of them, what percentage were actually on the drugs?
Well that was the 4.95%.
And notice this would give you the exact same result.
Now there's an interesting takeaway here.
Because this is saying,
of the people that test positive,
72% are actually on the drugs.
You could think about it the other way around.
Of the people who test positive.
495 plus 190, what percentage aren't on drugs?
Well that was 190,
and this comes out to be approximately 28%.
100% minus 72%.
If we were in a court of law
and let's say the prosecuting attorney,
let's say I got tested positive for drugs
and the prosecuting attorney says
look, this test is very good.
It only has a false positive rate of two percent
and Sal tested positive, he is probably taking drugs.
A jury who doesn't really understand this well
or go through the trouble that we just did might say,
oh yeah Sal probably took the drugs.
But when we look at this,
even if I test positive using this test,
there's a 28% chance that I'm not taking drugs.
That I was just in this false positive group,
and the reason why this number is a good bit larger
than this number
is because when we looked at the original division
between those who take drugs and don't take drugs,
most don't take the illegal drugs.
Two percent of this larger group
of the ones that don't take the drugs,
well this is actually a fairly large number
relative to the percentage that do take the drugs
and test positive.
So I will leave you there.
This is fascinating not just for this particular case,
but you will see analysis like this all the time
when we're looking at whether a certain medication
is effective or a certain procedure is effective.
It's important to be able to do this analysis.