The NovaSeq X series of systems is the newest
and most powerful of Illumina next generation sequencers.
The series offers two instruments, the NovaSeq X Plus with dual flow
cell configuration and the NovaSeq X with single flow cell configuration.
Let's meet the NovaSeq X Plus.
You may choose to set up your run in the cloud or on instrument
by navigating the 4K touchscreen or using the hidden keyboard and touchpad.
You may also include an analysis step during your run planning using onboard
DRAGEN or cloud applications, or use your own analysis pipeline.
If using onboard DRAGEN, you may select several different analyses
per flow cell, including BCL to FASTQ conversion
and application specific analysis for whole genome sequencing,
whole exome sequencing, and RNA sequencing.
After setting up your run, unbox your reagent kit,
we have reformulated more than a dozen of our reagents
to enable shipping with no dry ice and no ice packs
so you can change the world while minimizing your impact on the environment.
Because your reagent
kit arrives at room temperature, it's ready to use immediately.
If you'd like to start your run at a later time,
follow the proper storage conditions listed on each component.
Next, dispense your prepped libraries into each tube of the library tube, strip
after they have been neutralized and diluted with the provided preload buffer.
Your libraries will be automatically loaded into each lane of the flow cell
once the sequencing run begins.
The NovaSeq X series makes the most of every sample requiring
four times less library input than NovaSeq 6000's on board workflow.
Snap your filled library tube strip and the lyo insert into the reagent cartridge.
The lyo insert contains lyophilized reagents
that will be reconstituted on instrument.
After inserting the loaded library tube strip
and lyo insert into the reagent cartridge, you are now ready
to load your consumables.
The status bar and drawers will light up to indicate
where you should interact with the instrument.
Follow the prompts to easily empty the waste from the prior run
and load your preloaded reagent cartridge,
buffer cartridge and flow cell.
With up to eight individually addressable lanes per flow cell
and multiple output and read length options, The NovaSeq
X Series scales with you from pilot project to population scale sequencing.
The combination of hyper resolution optics,
blue green lasers, and ultra high density flow cells
enables you to sequence deeper at our lowest price per sample yet.
Throughout loading, the instrument verifies
that all RFID encoded reagents are compatible
and have been loaded properly, minimizing the chance of user error.
After a few minutes,
the pre run checks will complete and automatically initiate the run.
The NovaSeq X Series harnesses the accuracy, speed,
and robustness of our latest sequencing by synthesis chemistry,
X-LEAP, SBS Chemistry The NovaSeq X plus system allows you to run
one or two flow cells simultaneously, or staggered from one another.
The NovaSeq X system runs one flow cell at a time,
and is fully upgradeable to the NovaSeq X Plus system.
With the DRAGEN Bio-IT platform
and with pushbutton access to variant calling accuracy,
you can seamlessly transition from sample to result in less time.
Monitor the progress of your sequencing run and view detailed performance metrics
from the instrument or via the cloud, including anticipated time of completion.
If you have opted for onboard DRAGEN analysis
you may view your DRAGEN Report on instrument.
Following completion of your run, cartridges can be easily disassembled
and disposed of according to your local guidelines.
Access exceptional throughput and accuracy to perform larger studies,
more ambitious projects, and more data intensive methods.
You are ready to change the world.
With the NovaSeq X series, you can.