dorynase alpha is a mucolytic agent most commonly used for treating patients with
cystic fibrosis it's an inhaled drug that is administered in aerosol form
with a nebulizer in this video we will provide an overview of this drug
including its uses dosage side effects and more so if you're ready let's get into it
pulmozyme is the brand name for dorney's alpha which is a mucolytic agent used to help break
up mucus in patients with cystic fibrosis as previously mentioned it is administered with
a nebulizer which breaks up a liquid solution into tiny aerosol particles that can be inhaled
into the lungs this helps improve pulmonary function by decreasing the thickness of mucus
and decreasing respiratory tract infections dorne asapha works by hydrolyzing dna that is present in
mucus which helps thin it out so that it's easier to cough up for removal as previously mentioned
during ace alpha is most commonly used for the treatment of patients with cystic fibrosis cystic
fibrosis is a chronic obstructive disease that affects the lungs and digestive system it often
results in lung infections and copious amounts of thick secretions that make it difficult for
patients to breathe this is why dornades alpha is often indicated to help break up these secretions
cystic fibrosis causes an increased sodium and chloride concentration in the sweat glands
which explains why patients often have salty tasting skin with this disorder and as the disease
progresses it causes malnutrition and severe weight loss the standard dose of dornae's alpha
for adults when administered via nebulization is 2.5 milligrams once per day however adult
patients with a forced vital capacity greater than 85 percent may benefit from the 2.5 milligram dose
via nebulizer twice per day for the most benefit it is recommended that patients inhale dornase
alpha approximately 30 minutes before receiving airway clearance therapy this gives the medication
enough time to help break up thick mucus so that it's easier to remove dornae's alpha is
effective in helping break up mucus but it can also cause a few adverse side effects
including chest pain hoarseness fever indigestion pharyngitis rhinitis rash and conjunctivitis
dornance alpha is contraindicated in patients who are allergic or sensitive to the drug therefore it
should not be administered to patients who have had hypersensitivity reactions after taking it
and you may be wondering what exactly is a mucolytic agent well mucus is a sticky
vicious substance that is produced by the mucous membranes it serves an important role
by trapping foreign particles and bacteria which prevents them from entering the body
however mucus can also build up and cause problems especially in people with respiratory conditions
this is when mucolytic agents would be indicated because they work to dissolve mucus which makes
it easier to expectorate the two primary types of mucolytic agents are acetylcysteine
aka mucomist and dornaes alpha aka pulmozyne mucomist is a similar inhaled drug indicated
for the treatment of bronchopulmonary secretions and is known for its distinct foul-smelling odor
check out the links below if you want to learn more about mukmist but if you do want to support
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and just a quick reminder we are not doctors this video is for informational purposes only
thank you so much for watching have a blessed day and as always breathe easy my friend you