you're lying in bed drifting off to
sleep when suddenly you're jolted awake
by a startling loud noise except
that noise is just in your head welcome
to watch mojo and today we're counting
down our picks for the top 10 diseases
that can't be explained a regular
routine from many agonizing for rod
palmitier feels like my tongue has been
burnt for this list we'll be looking at
bizarre and rare diseases that betray
our understanding of the human body we
will be defining disease in a broad
sense to include any condition that
causes pain discomfort or dysfunction
within the body which of these do you
find the scariest let us know in the
comments
number 10 alice in wonderland syndrome
be honest alice in wonderland syndrome
is a pretty mind-bending condition
literally this neuropsychological
condition takes its name from lewis
carroll's iconic novel and directly
references one experience in particular
though suffering from alice in
wonderland syndrome or dysmotropsia
experience an impaired sense of
perception patients can report things as
looking longer than they should be or
slowing down in time things seems to be
slow or fast some patients report they
can't even see motion objects appear
smaller or larger than they actually are
not to mention closer or farther away
basically it makes you feel like alice
after she drinks the mysterious potion
this condition is typically associated
with head injuries and migraines but no
one really knows what causes it one
leading theory is that an abnormally
large amount of blood is sent to the
area of the brain that processes
perception resulting in a warped sense
of reality but again this is just one
theory among many oh dear i do wish i
hadn't cried so much number nine foreign
accent syndrome this is an incredibly
rare condition between 1941 and 2009 the
medical community documented just 62
confirmed cases of foreign accent
syndrome and
i was a bit concerned and i with ill
health i tend to get over fatigued so i
thought it would stop when an individual
acquires this condition they begin
speaking in what sounds like a different
accent i am looking forward to digging
into those large fries with the ketchup
and the milkshake sound a little bit
irish maybe maybe well how irish are you
um i've never been to ireland in my life
however it's not like a midwestern
american suddenly wakes up with a
flawless welsh dialect rather this
syndrome relates to an altered type of
speaking that is only perceived as a
different accent was it a bit of a
novelty for you early on
a little bit
but mostly it was just a bit confusing i
think i never realized how you sound is
actually really quite a part of your
identity the medical community doesn't
really know what causes fas but it's
likely due to significant damage in the
left hemisphere of the brain as a result
the syndrome typically becomes
pronounced after serious head trauma or
more commonly a stroke i could hear the
nurses laughing in the hallway because
they didn't think that this was real
number eight hutchinson-gilford progeria
syndrome
simply known as progeria this is an
extremely rare disorder that causes
premature aging in young children kaylee
how old are you
now you're six and and in july you're
going to be
seven
seven that's a big girl victims
experience significant developmental
delays before physical symptoms become
pronounced those suffering from progeria
are typically short bald and have a
disproportionately small face everybody
has their own obstacles in life
you know whether they be daily obstacles
or you know
whatever frequency they are and
for me i just take them as they come
progeria typically takes the victim
around 13 or 14 years old what we do
know is that the disease is caused by an
abnormal protein called progerin but no
one knows why the disease causes rapid
aging it's believed that compounds
called free radicals cause premature
damage to the cells resulting in their
impaired function either way this is a
horrible disease that affects one in 18
million children and and what do you
hope what do you hope is going to happen
i hope and
if i grow hair and
i feel curly hair number seven
morgellons delusional parasitosis
morgellons is not actually recognized by
the medical community those purportedly
suffering from morgellons tend to
self-diagnose and claim that they have
skin lesions containing some sort of
unnatural fibrous material the x-files
it's nothing short of that the medical
community believes that this is a form
of delusional parasitosis in which
victims believe that bugs or parasites
are living under their skin just why
people believe this is not known they
say people who claim to have it are
delusional conjuring up parasites
scratching themselves even planting
textiles like cotton on themselves to
feed the delusion the leading theory is
that the brain is overloaded by dopamine
due to a malfunctioning dopamine
transporter this transporter can break
down from a variety of diseases and
infections or from harmful stimulants at
times though this delusion may be a part
of others psychosis schizophrenia
bipolar affective disorder or a major
clinical depression this is why
delusional parasitosis is often
associated with cocaine use and is
informally known as cocaine bugs
number six dancing mania
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many people have heard of the bizarre
dancing plagues occurring between the
14th and 17th centuries these were
outbreaks of random dancing that
occurred in thousands of individuals
across europe and this wasn't fun
dancing it was dancing to the point of
physical exhaustion and collapse and
maybe even injury
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to this day no one has any idea what
these plagues were about some claim that
the dancing was meant to alleviate
stress and that it wasn't a disorder at
all others believe they were staged by
religious cults and some believe it was
a genuine illness caused by ergot
poisoning or epilepsy contemporary
sources had no idea what caused it and
unlike virtually everything else from
medieval europe that knowledge has not
improved
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number five burning mouth syndrome you
know that intense feeling you get after
eating something spicy well imagine
living with that for years or even for
the rest of your life and you have
burning mouth syndrome we think it
happens because the nerves misfire and
therefore you get these funny sensations
it can actually be quite painful
sufferers of this bizarre condition feel
a scalding or tingling sensation in
their mouths that cannot be alleviated
and does not have a medical cause this
is not a harmful condition but it tends
to negatively affect the quality of life
and as such is typically treated with
antidepressants very uncomfortable just
to be sitting
doing nothing english pop singer sheila
chandra was forced to retire due to this
condition as simply speaking causes her
great pain no one has any idea what
causes bms and there is no known cure
there is not a lot of definitive
understanding as to what causes it what
are the best ways to treat it number
four sweating sickness
and here we have yet another mysterious
disease that struck europe throughout
the 15th and 16th centuries the sweating
sickness began with great limb pain and
violent cold shivers when you get an
infection sometimes your brain will say
okay as part of our reaction to this
let's turn up the heat
that's when oftentimes you'll develop
chills and shivering because your body's
literally trying to heat itself up right
after an hour or two people would break
out in heavy sweat experience an
unquenchable thirst and grow delirious
before collapsing or dying all this
occurred in just one day and came
completely out of the blue the last
recorded outbreak occurred in 1551
although france experienced something
similar as recent as 1918 no one has any
idea what caused it but theories range
from an unknown hantavirus to the poor
sanitation of the time
living back then really did suck
number three pica one of the most
peculiar disorders on this planet is
pica which occurs both in humans and
other mammals pica is the desire to eat
objects that are not food and do not
have any nutritional value i'm addicted
to eating dry wall
this can include the likes of drywall
glass wood and even more disgusting
things like urine and feces while pica
is not harmful in itself the objects
that a victim swallows can do great
damage to their bodies and intestinal
tracts i would normally take a piece
like this
and normally just put it in my mouth or
bite on it i just put the whole piece in
my mouth and
pica is currently categorized as a
mental disorder and the exact causes are
up for debate some believe it has
something to do with ocd and
schizophrenia while others think it
arises from mineral deficiencies in the
blood we just know that mineral levels
can be low in in some of these patients
and you know maybe that's actually an
after effect the fact that they're
eating non-nutritive substances number
two aquagenic urticaria more simply
known as water allergy aquagenic
urticaria proves that humans aren't
meant to be in the water well some
humans anyway those suffering from water
allergy will break out in hives after
coming into contact with water this
occurs with all forms of water and with
any temperature even sweating or crying
can result in hives as the water content
found within sweat and tears is enough
to cause an outbreak the couple says
little ivy can only be in the water for
up to 15 seconds before her skin starts
to burn and develops blisters the hives
may itch and they typically disappear
after an hour or so there is no known
cure for this phenomenon aside from
avoiding water that is any surface that
the tear touches will become itchy and
it often comes up red on my face as well
and yes that means no baths or showers
and best of all no one has any idea what
causes it it's just one of those things
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number one exploding head syndrome for
something so widespread it's funny how
few people have even heard of exploding
head syndrome this is a sleep disorder
where victims hear very loud noises when
either falling asleep or waking up an
air horn
an explosion
a gunshot
imagine being awakened by one of these
from a sound sleep some even report
accompanying visual disturbances like
flashes of bright light what's truly
fascinating is that one in every 10
people reportedly experienced this
phenomenon the good news is that despite
the horrifying symptoms the syndrome is
not dangerous and reassurance is often
enough to alleviate the resulting
anxiety i've heard of of cases where
people had it up to seven times a night
so you can imagine that would cause an
enormous amount of sleep disruption
however exploding head syndrome has no
known cause although it's likely due to
some type of harmless dysfunction in
what is called the reticular formation
so instead of shutting down your
auditory neurons when you're going to
sleep for some reason they all fire at
once and that's why you get this really
loud noise this plays a major role in
our brain's ability to process sleep and
consciousness do you agree with our
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you