Sal: ATP or adenosine triposphate is often referred to as
the currency of energy, or the energy store, adenosine,
the energy store in biological systems.
What I want to do in this video is get
a better appreciation of why that is.
Adenosine triposphate.
At first this seems like a fairly complicated term,
adenosine triphosphate, and even when we look at its
molecular structure it seems quite involved, but if we break
it down into its constituent parts it becomes a little bit
more understandable and we'll begin to appreciate why,
how it is a store of energy in biological systems.
The first part is to break down this molecule between
the part that is adenosine and the part that
is the triphosphates, or the three phosphoryl groups.
The adenosine is this part of the molecule,
let me do it in that same color.
This part right over here is adenosine,
and it's an adenine connected to a ribose
right over there, that's the adenosine part.
And then you have three phosphoryl groups,
and when they break off they can turn into a phosphate.
The triphosphate part you have, triphosphate,
you have one phosphoryl group, two phosphoryl groups,
two phosphoryl groups and three phosphoryl groups.
One way that you can conceptualize this molecule which will
make it a little bit easier to understand how it's a store
of energy in biological systems is to represent this whole
adenosine group, let's just represent that as an A.
Actually let's make that an Ad.
Then let's just show it bonded to
the three phosphoryl groups.
I'll make those with a P and a circle around it.
You can do it like that, or sometimes you'll see it
actually depicted, instead of just drawing these
straight horizontal lines you'll see it depicted
with essentially higher energy bonds.
You'll see something like that to show
that these bonds have a lot of energy.
But I'll just do it this way for the sake of this video.
These are high energy bonds.
What does that mean, what does that
mean that these are high energy bonds?
It means that the electrons in this bond are in a
high energy state, and if somehow this bond could be
broken these electrons are going to go into a more
comfortable state, into a lower energy state.
As they go from a higher energy state into a lower, more
comfortable energy state they are going to release energy.
One way to think about it is if I'm in a plane and
I'm about to jump out I'm at a high energy state,
I have a high potential energy.
I just have to do a little thing and I'm going
to fall through, I'm going to fall down,
and as I fall down I can release energy.
There will be friction with the air, or eventually
when I hit the ground that will release energy.
I can compress a spring or I can move a turbine,
or who knows what I can do.
But then when I'm sitting on my couch
I'm in a low energy, I'm comfortable.
It's not obvious how I could go to a lower energy state.
I guess I could fall asleep or something like that.
These metaphors break down at some point.
That's one way to think about what's going on here.
The electrons in this bond, if you can give them just
the right circumstances they can come out of that bond
and go into a lower energy state and release energy.
One way to think about it, you start
with ATP, adenosine triphosphate.
And one possibility, you put it in the presence of water and
then hydrolysis will take place, and what you're going to
end up with is one of these things are going to be essentially,
one of these phosphoryl groups are going to be
popped off and turn into a phosphate molecule.
You're going to have adenosine, since you don't
have three phosphoryl groups anymore, you're only
going to have two phosphoryl groups, you're going to
have adenosine diphosphate, often known as ADP.
Let me write this down.
This is ATP, this is ATP right over here.
And this right over here is ADP, di for two,
two phosphoryl groups, adenosine diphosphate.
Then this one got plucked off, this one gets plucked
off or it pops off and it's now bonded to the oxygen
and one of the hydrogens from the water molecule.
Then you can have another hydrogen proton.
The really important part of this I have not drawn yet,
the really important part of it,
as the electrons in this bond right over here go into
a lower energy state they are going to release energy.
So plus, plus energy.
Here, this side of the reaction,
energy released, energy released.
And this side of the interaction
you see energy, energy stored.
As you study biochemistry you will see time and time
again energy being used in order to go from ADP and
a phosphate to ATP, so that stores the energy.
You'll see that in things like photosynthesis
where you use light energy to essentially,
eventually get to a point where this P is put back on,
using energy putting this P back on to the ADP to get ATP.
Then you'll see when biological systems need to use energy
that they'll use the ATP and essentially hydrolysis
will take place and they'll release that energy.
Sometimes that energy could be used just to generate heat,
and sometimes it can be used to actually forward
some other reaction or change the confirmation of
a protein somehow, whatever might be the case.