This video is sponsored by our friends at OneSkin.
Learn more about how they’re working to reverse skin aging at the end of this video!
Since this channel is 10 years old, which is 6000 in internet years, my appearance isn’t
as perfect as it once was.
Lately, I’ve been getting digital wrinkles removed by Animator, and as I was getting
photoshopped it made me think of you humans and your fragile skin.
That sounded less weird in my noggin.
Hmm..uh, Let me try again!
I want to discuss your body.
Nope.
uh…Hold on.
Your Epidermis is under attack!
No.
Too clickbaity.
Just cue the intro, I’ll figure something out!
Hey there!
Welcome to Life Noggin!
As the largest organ, the skin has a lot of jobs.
It contains nerve receptors that allow you to feel, it controls your water and electrolyte
balance and your body temperature, and it protects you from the environment.
Your skin is just giving you a giant hug if you think about it.
Don't think about actually.
Now that i think about it, that's kinda weird!
I wasn’t really kidding before about your skin being under attack.
As you age, your skin goes through a lot of changes.
These are caused by the environment, your genetics, and your nutrition.
The number one factor influencing your skin is ultraviolet light from the sun, but things
like pollution and smoking play a large role as well., And all parts of your skin are affected.
The skin can be divided into three main layers: the top or the epidermis, the middle or the
dermis, and the bottom or the subcutaneous layer.
Each of these experiences changes as you age.
For example, the pigment cells in your epidermis can become disordered, leading to dark spots
or uneven skin.
The subcutaneous layer loses fat, which makes you colder and more prone to injury.
And in the dermis, the important proteins that give the skin strength and flexibility–collagen
and elastin break-down, resulting in weak and wrinkled skin.
One of the main causes of this is the build up of old cells called senescent cells.
When a cell reaches the end stage of its life cycle, it stops dividing and is often killed
off.
But sometimes they remain in your body, becoming senescent cells.
They should start paying rent if they’re gonna just stick around like that!
As you age and your immune system becomes less efficient, more and more of these senescent
cells accumulate.
And even though they’ve stopped multiplying, they’re still active.
While some are harmless or even beneficial, others can secret chemicals that cause inflammation,
suppress the immune system, and cause nearby cells to age faster.
Many of these cells build up in the skin, compromise collagen production, cell renewal
and weaken the skin’s protective barrier, eventually leading to visible signs of aging
such as wrinkles and skin sagging.
We obviously don’t want that.
So, what the heck do we do!?
Well, what if we could eliminate senescent cells?
Give ‘em a 1-hit KO.
Sorry.
Don't know why my voice did that!
Studies on rodents, and even on a small number of humans, have found that treatments that
kill senescent cells–called senotherapeutics–reduced inflammation, increased health span, and delayed
the onset of age-related diseases.
While these treatments are being explored to treat age-related illnesses like osteoporosis,
glaucoma, and diabetic neuropathy - one company in particular, OneSkin, has developed a topical
senotherapeutic to directly combat skin aging.
They developed a peptide named OS-01 that was found to reduce the number of senescent
cells in live skin cultures by up to 50%.
At the same time, OS-01 helps to renew healthy cells, so they can build up healthy skin and
jumpstart our beloved collagen production again.
And this video happens to be sponsored by our smart friends over at OneSkin!
OneSkin is the only longevity brand scientifically proven to reverse skin aging.
OneSkin's line of topical skin products are powered by the first ingredient proven to
reverse skin's biological age, targeting the root cause of skin aging to improve its longevity
for long-term, visible results.
Founded by a team of longevity scientists, OneSkin's approach is research-first and their
proprietary peptide is scientifically validated to improve skin's barrier function and promote
cellular repair pathways.
Experience the benefits for yourself!
Click the first link in the description, or use the code LIFESPAN at checkout to save
15% on your first order.
Click here to watch that video we did on senescent cells or click here to watch this mystery
video!
I don't even know what it is, it's just gonna pop up!
Do all the things that help this channel grow!
We really appreciate it!
and if you're into the topic of longevity as a whole, then you definitely need to check
out the team that powers Life Noggin, Lifespan, down in the description!
as always my name is Blocko, this has been life noggin, don't forget to keep on thinking!