The film opens somewhere south of Colombia
Crime boss Elijah Clarke meets with a local drug lord Santiago
and his son Jeronimo, who presents him with a superweapon
that is capable of accessing networks and computer systems all around the world
They demonstrate it by controlling a plane flying overhead
Impressed with the weapon
Clarke and his goons kill Santiago and Jeronimo in an attempt to take it for himself
but police soon raid the area forcing Clarke to flee
Government agent Luis Rojas finds the drive containing the weapon and he takes it
Back at the CIA headquarters in Langley
the higher-ups learn about Luis taking the drive and that he is
willing to sell it in order for him and his family to get away to safety
Director Larry Marks approaches Agent Mason
“Mace” Browne and her partner Nick Fowler about recovering the drive
The two plan a cover story in which they are a couple on their honeymoon,
but there is a legitimate attraction between the two agents
Mace and Nick travel to Paris and go to a cafe where Luis is waiting to make a drop
Their bag is intercepted by another agent Marie Schmidt, who is posing as the cafe server
Marie flees on a motorcycle and Mace chases after her, while Nick runs after Luis
Mace follows Marie all the way down into the subway,
where Marie manages to hop on a train and get away
but she is dismayed to find that the package she got
was the money that Mace and Nick were going to give Luis
Meanwhile, Nick chases Luis through the streets, but Nick loses him
and ends up in an alley where he is confronted by Clarke
and one of his goons, who ask Nick if he has the drive
Nick tells them no, so Clarke orders his men to kill him
Luis goes to his room where he is met by a psychologist Graciela Rivera
She tries to ask him where he is keeping the drive as she knows he can trust her
At the same time, Marie meets with her boss
Jonas Muller as they gather their information on Mace and Nick
Despite Jonas trying to keep Marie where she currently is,
she persuades him to let her go after the drive
He tries to convince her that she needs a team, but Marie refuses
And She tells him that he trained her to chase a mission to the end,
and Jonas let her complete to the mission
Mace returns to Langley, where she is interrogated by the agent,
because of missing the 3 million dollars And when she asked about Nick
Marks tells her that Nick was shot dead, leaving her distraught
After stopping the camera by Marks, he tells Mace to go and find the drive herself
She travels to London to reunite with an old friend cyber intelligence expert Khadijah
After sitting through a presentation of hers
Mace tries to get Khadijah to join her on the mission,
but she says she is done with the work, they used to do
She is living happily in London with her partner Abdul
After Mace explains the severity of the mission,
and why the drive falling into the wrong hands could lead to World War III
and Khadijah helps Mace gather intel on Marie and Luis to track the latter
Mace and Khadijah track Luis and Graciela to a factory, where Marie is also looking for them
As they start closing in on Luis one of his fellow agents turns on him and shoots him,
while Mace fights Marie
Khadijah goes after the shooter, who gets away on a boat after being pursued by Mace and Marie
Graciela stays by Luis’s side as he dies,
and he gives her a phone that can be unlocked with her fingerprint
Marie finds Graciela and brings her to a safe house, but they are found by Mace and Khadijah
Mace and Marie have a standoff that is quelled by
Khadijah as they agree to put their differences aside to work together
Using Luis’s phone and Graciela’s fingerprint
Khadijah tracks the shooter to Morocco
The ladies go to Marrakesh, and track the villain in a market but, there are men following him too
Marie and Mace manage to kill them all
After following him through a crowd, and managing to get by unnoticed,
they intercept the drive and get it to safety
Khadijah decrypts what is on the drive, and they later arrange to hand it over to Marks
Afterward, the ladies go out for drinks, where they bond and learn that Marie’s father
was a double agent for Russia, and that she had to turn him in
Back at CIA HQ, a woman enters and attacks Marks before shooting him dead
later, The ladies watch news reports of multiple plane crashes
and power grids being shut down in two cities
and They realize that the drive has indeed fallen into the wrong hands
They return to HQ, to find Marks dead before other CIA agents led by Grady come to get them
The ladies get the advantage and disarm the agents before making their getaway
Marie asks Jonas to help them
he orders her to come back, but it seems that he is forced to say that,
and he must make the call more than 40 seconds, so they can find her location
Marie reveals that, and breaks the phone before finding her location
They locate the shooter and take him captive to pry information out of him
Marie shoots him in the leg, where he could bleed to death
unless he tells them what they want to hear
The shooter relents and tells them about an auction happening in Shanghai
and They put a tourniquet on him so he won’t die
The team heads there to go to the auction in disguise
One thug tries flirting with Graciela, who is gaining her first experience in the field
Mace is also surprised when she discovers that Nick is alive
However, she soon learns that he is working with Clarke and is there for the drive himself
Mace fights one of his goons, while Nick sits in for the auction
later, He finds that the woman who killed Marks is with her father as they hold the drive
He takes the drive after buying it just as the police arrive when Marie creates an explosion
The woman then calls the officers off
before Nick leaves, Mace holds him at gunpoint,
but Nick says if she shoots his men will shoot at the crowd
after he leaves, the police arrive and they try to escape
but the woman shows again, and brings the ladies to meet with her
she introduces herself as Lin Mi Sheng an agent with China, who has also been tracking the drive
She informs the ladies, that Marks was in on the scheme with Clarke
Lin and her father have gathered intel on several criminals, who were
at the auction including the one who was flirting with Graciela
she also reveals that she has the real drive
When Clarke finds that Nick doesn’t have the drive, he has his men beat Nick up
later, Nick and his goons track the ladies to their safe house
They show them separate screens showing that his men have also located Abdul
Jonas and Graciela’s husband and children
and they are all being held at gunpoint
Nick shows he is not messing around by having his men kill Lin’s father, Jonas and then Abdul
but the ladies relent and give him the drive before they can kill Graciela’s family
Nick and his guys take the drive, as well as Lin so she can operate the drive
After the ladies grieve their losses
they resolve to go after Nick
when they find that Lin’s glasses have a camera, that allows them to see where she is going
Nick brings Lin to his hotel, and forces her to decrypt the drive,
while the rest of the team stages an assault
They engage in a shootout with Nick’s goons and Lin manages to fight back as well
After killing most of them, Mace fights Nick, who shoots Marie in the shoulder
and nearly kills Mace before Graciela shoots him
Authorities come to arrest the women, but Khadijah destroys the drive first
Two months later, Nick tracks Clarke down and shoots him dead
He weasels his way back into the CIA as the new director
with Grady helping him track down Mace and the others
since they are reported as being on the run
Mace eventually finds Nick herself in his home, and is joined by Khadijah, Graciela, Marie and Lin
They slip Nick a poison in his drink
and tell him they plan to turn him in to be placed in an international prison for his crimes
The ladies leave and part ways
until they are called to work together again