Hey, what's wrong? I'm trying to lose weight but nothing I try works, I just can't do it. Here try
this. Michael's Secret Stuff? Well, I guess it's worth a shot, I've tried everything else. It
worked! Sorry guys, I couldn't resist. There are so many different magic pills,
fad diets out there, each trying to come up with some new way to get you to lose weight and somehow
none of them work. To me, it's amazing how some people go to such extreme lengths to lose weight,
and ignore a basic biological principle. Right now I am going to show you a very simple trick
that you can implement today that doesn't cost any money and you won't even have to starve yourself.
It's based on the proper understanding of three chemicals in your body. A peptide called ghrelin,
a hormone called leptin, and a neurotransmitter called dopamine. understanding how these three
chemicals interact in your body you can then make a simple change to get the results you want. Let's
take a look at how this works. What's up everyone I'm Michael Kamalu, Medical student at the Mayo
Clinic I've had a lot of people ask me for nutritional advice and how to cut and lose weight
and while you have likely heard of a thousand different strenuous diets or "magical weight loss
pills" I never advise nor do anything myself that is not healthy, sustainable in the long term, and
proven by medical science. And that guys is the key ingredient to Michael's Secret Stuff. Proper
understanding of how your body actually works and leveraging that you reach your goals. In this
case, there is a very simple strategy for losing weight for those of us who have a tendency to eat
just one too many cookies. let's walk through that cookie. When you eat the tastebuds in your
tongue sends signals to your brain which releases the neurotransmitter called Dopamine which is
responsible for pleasure and drive. This dopamine hitting the brain results in the thought, "that
was good. I want another one." meanwhile this cookie makes its way down your esophagus to your
stomach. Now, why do we eat in the first place? Because we feel hungry. What actually causes
that hunger? Well, when your stomach is empty it produces a hormone called Ghrelin. Ghrelin is a
peptide hormone that travels in the bloodstream up to your brain. There it hits a structure
called the Hypothalamus which recognizes that you are energy deficient and thus need to eat. Now,
what happens when your meal starts filling your stomach it expands. All those little ridges you
see in there flatten out. Through a complicated process that we don't need to go into this
stretching of the stomach signals to those cells to stop producing Ghrelin, but here's the catch:
because ghrelin is a hormone and has to travel all the way from your stomach to your brain,
it takes a solid 10-15 minutes for your brain to recognize that your stomach has stopped producing
Ghrelin. And if you are like me, you can eat a lot of cookies in 15 minutes. If you take a
minute to think about it, you almost certainly have experienced this phenomenon. Your hungry,
there are cookies, you eat one. Dang, that was good. There is that dopamine release in your
brain. So you eat another one. You feel like your starving and you can eat the entire box
of cookies. But before you can reach for another one you get distracted for a little bit, and after
5-10 minutes you come back and realize that you are actually not that hungry anymore. That right
there is the magic of understanding Ghrelin. So I told you the solution to overeating is simple,
and here it is: whatever you are eating eat more slowly. Take a few seconds between each bite.
Give your stomach the time to expand and send the signal to your brain that you have eaten enough.
We were all born with an incredibly intelligent body that knows exactly how much energy it needs
to function at an optimal level. We just need to learn how it works and work with it, not against
it. Now, where does Leptin come in? You may or may not have heard about leptin supplementation
for weight loss. Leptin is a hormone secreted mostly by adipose, which is another name for
fat cells and has the opposite role of ghrelin. It tells your brain that you are full, or have
enough energy storage. Some people have started marketing leptin supplements as a way of tricking
your brain into thinking you are full. Here's why that doesn't work: a study published back
in 2006 found that ghrelin, the hunger hormone actually blocks the leptin pathway through the
hypothalamic MPY1 pathway. You don't need to know what is or what the means, other than if you are
legitimately hungry-your stomach is empty and producing ghrelin, that ghrelin will keep leptin
from having any action on your hypothalamus. And thus the leptin supplementation does nothing. so
the secret my friends is not to starve yourself. All this hype about intermittent fasting or
juice cleanses may have their place and their benefits, but what I advocate for is long term
sustainability. One of my personal mottos is don't eat less, eat smarter. And as we just learned that
not only includes what foods you are eating but the rate at which you are eating it. Guys if you
thought that was helpful please leave me a like or a comment, share with any of your friends who have
wanted to lose weight but have been unsuccessful with all the fancy fads there is a lot more where
this came from so make sure you subscribe so you don't miss any of these videos, if you have
any questions you can reach out to me on Instagram @GainsWithoutPains_MD and I will talk to you then.