Thank you for your interest in SeedEZ 3D cell culture system.
In this video we will show you a liver 3D culture model.
Watch how HepG2 human hepatocellular carcinoma cells grow in 3D in SeedEZ for up to 4 weeks.
After 1 week in culture, 3D cell aggregates continue to grow and merge, forming larger
hepatospheres and other aggregate shapes. In 3 to 4 weeks, an engineered liver tissue
is formed in SeedEZ. Liver 3D culture is a useful model for in
vitro toxicology and ADME/Tox screening. Liver specific functions, expression and secretion
of drug metabolizing enzymes decline rapidly in 2D culturing conditions. Studies suggest
that by culturing liver cells in 3D as organotypic aggregates preserves these functions.
Let SeedEZ take you on a journey from a cell, to spheroid, to engineered tissue and beyond.