In todays video we discuss what happens when you eat too much protein. Roll the titles.
Hey everyone. Welcome back to the channel. As always just a quick reminder that I'm
now offering the SIBO, organic acids, stool test and consult via my website.
So if you have any health or digestive issues then consider taking these tests
as they will offer a lot of useful information upon which you can start making informed decisions
and then start getting your health back on track. And on that bombshell, to the video.
Now the goal for most of us is to live as long as possible and be as healthy as
possible in those years. Now there are many factors that will determine our success.
Genetics, DNA damage, telomere length, IGF-1, mtor, autophagy activity and so on.
Now we know from science that some of the best ways to improve our longevity prospects
are intermittent fasting as this has been shown in conjunction with a healthy diet
to increase telomere length, induce autophagy,
help protect us from DNA damage, as well as down regulate MTOR, growth hormone, and IGF-1.
The catch 22 for people who are looking to building muscle and resistance train is that
you need to eat additional protein and activate pathways such as MTOR, growth hormone and IGF-1
in order to build that muscle. So there is a potential trade-off between trying
to grow muscle and not causing MTOR, growth hormone and IGF-1 to become too elevated……as
there are established links with these and diseases such as cancer.
So before I delve specifically into protein and why I wont
take protein powders I first need to discuss IGF-1 and MTOR in a bit more detail……because
if the goal of us all is to live a long and healthy life
then we need to understand where these fit in around longevity and protein intake.
So there is a lot of research that shows established links and correlations between
HIGH igf-1 levels and cancer rates. And you can see this specifically in some
humans who have mutations in their genes that regulate IGF-1
which cause them to have higher levels of IGF-1. These people with genetic mutations tend to have
higher cancer rate incidence compared to wider populations.
The theory is that IGF-1 is a growth signal that causes cancer cells to proliferate very quickly.
So when you have accumulated damage in your cells from everyday life,
so that could be mitochondrial damage or genomic damage,
then there are signalling pathways that say we have too much damage in this cell
therefore we need to kill it off ASAP before it can mutate into a cancerous cell.
Now the signalling pathway for killing off the cell is called apoptosis……and
this essentially means that the cell is flooded with different things such as calcium
to destroy the cell in its entirety.
Now the problem arises when you have too much circulating IGF-1
because when IGF-1 is present it overrides apoptosis and says no no no
forget about the damaged cell we want growth so therefore for keep growing.
So this is why having high levels of LGF-1 can become very dangerous because it overrides
killing off a potentially cancerous mutations. Now I’m oversimplifying this slightly because
obviously the immune system is also involved in sweeping up rogue cells…..but you get my point.
So brining this back to protein……protein up regulates IGF-1 in the body. Now some types
of protein will up regulate this to a greater extent……but regardless even if you are on a
good clean source of protein, overdoing it cause higher rates of circulating IGF-1.
Another massive problem with high levels of IGF-1 is that it helps regulate and
switch off the FOXO gene which essentially turns off the repair mechanisms in the body
such as stem cell production and also things like autophagy.
But it's not all bad. Igf-1 is obviously important in the body and is essentially
for neurone production in the body which is call neurogenesis and it is also a really important
signalling pathway for muscle growth. Now to bring this all back around to
my point of this video of why I will never take protein powder.
So when you exercise it helps pull the circulating IGF-1 into the brain and muscles to assist in
its important functions in the body. And that is all very well when you are exercising regularly.
The problem arises when you are on a high protein diet
and lead a fairly sedentary life. So for me if I were to eat a high protein diet and it up
regulated IGF-1 and caused my circulating levels to increase then because I am not exercising and
pulling IGF-1 into the brain and muscles then I leave myself susceptible to apoptosis override.
So all the time the IGF-1 is being used up then no problem……the minute the IGF-1 is building
up in your system and is actually as a strong signalling pathway for growth for damaged cells
then you maybe playing with fire, especially if you have a poor immune function.
So quite simply if you are on a high protein diet or you are loading up on protein powders then
you better make sure you are exercising enough
to create a need for that excessive IGF-1 in the body.
And another tip for you if you are loading up on protein powders and other forms of protein,
I would highly recommend a 48 hour fast
once a month of so. Doing this will drive down any excessive IGF-1 in the body
which will in turn activate things like autophagy and clear out any damaged cells.
So that’s the end of today’s video, I hope you all enjoyed and as always
remember to look after your body because it’s the only place you have to live.