>>>
>>> APRIL
>>> APRIL 11 SGT. WORLD
WORLD
WORLD PARKINSON'S DAY.
PARKINSON'S DAY. TEN MILLION
TEN MILLION PEOPLE WORLDWIDE ARE LIVING WITH
PARKINSON'S.
PARKINSON'S. IT'S MEANT TO RAISE
AWARENESS ABOUT THE PROGRESSIVE
NERVOUS SYSTEM DISORDER AND
GIVES PEOPLE A VIEW OF WHAT IT'S
LIKE.
LIKE.
LIKE. >>
LIKE. >> WE'RE HERE TO DISCUSS THE
LATEST BREAKTHROUGHS AND
DIAGNOSES IN PARKINSON'S.
LET'S
LET'S
LET'S TALK ABOUT THE BASICS OF
PARKINSON'S.
PARKINSON'S. YOU WERE SAYING THE
DIAGNOSIS IS REALLY THE KEY FOR
MOST PEOPLE TO, MAKE SURE THEY
ARE GETTING AN ACCURATE
DIAGNOSIS.
DIAGNOSIS. >> YES.
>> YES.
>> YES. PARKINSON'S DISEASE
PARKINSON'S DISEASE CAUSES SYMPTOMS THAT MOST PEOPLE
KNOW OF, TREMOR AND SHUFFLING
GAIT.
GAIT.
GAIT. BUT
GAIT. BUT THERE ARE ALSO
SYMPTOMS SUCH AS SLOWNESS OF
MOVEMENT, STIFFNESS OF MOVEMENT.
AND REALLY MUCH MORE RECOGNIZED
COGNITIVE DYSFUNCTIONS, MOOD
DISORDER, ANXIETY, SLEEP
DISTURBANCES AND HALLUCINATIONS.
BUT THERE ARE OTHER -- BECAUSE
THERE'S NO BLOOD TEST OR BRAIN
IMAGING TEST TO DIAGNOSE
PARKINSON'S, AND THERE ARE OTHER
DISORDERS THAT CAN CAUSE
TREMORS, LIKE STROKE, THAT CAN
MIMIC SOME OF THE SAME SYMPTOMS.
AND OF COURSE THOSE TREATMENTS
ARE DIFFERENT.
ARE DIFFERENT. IT IS IMPORTANT
TO MAKE SURE YOU HAVE THE RIGHT
DIAGNOSIS SO YOU CAN GET THE
RIGHT TREATMENT.
RIGHT TREATMENT. >> YOU HEAR ABOUT PARKINSON'S A
LOT, RIGHT?
LOT, RIGHT? ACTORS HAVE COME OUT
AND SAID THEY HAVE.
CAN YOU
CAN YOU
CAN YOU TELL US WHAT IT IS?
>> PARKINSON'S DISEASE
SPECIFICALLY IS A
NEURODEGENERATIVE DISORDER.
NEURODEGENERATIVE DISORDER. SO
SO
SO THE
SO THE BRAIN CELLS IN PARKINSON'S
THAT PRODUCE DOPAMINE DEEP DOWN
IN THE BRAIN, THE BASAL GANGLIA,
DEGENERATE FOR SOME UNKNOWN
REASON.
REASON.
REASON. WE DON'T REALLY KNOW
WHAT THE TRIGGER IS.
BUT ONCE
BUT ONCE
BUT ONCE THEY START TO DEGENERATE, THEN
THEY LOSE CONTROL OF MOTOR
FUNCTION WHICH IS WHAT THAT PART
OF THE BRAIN CONTROLS.
>> RIGHT.
>> RIGHT.
>> RIGHT. >> YOU'RE TALKING ABOUT THE DEEP
BRAIN STIMULATION.
BRAIN STIMULATION. THERE ARE
THERE ARE
THERE ARE THESE DEVICES THAT PEOPLE WITH
PARKINSON'S MAY HAVE IMPLANTED
THAT WILL PROVIDE THEM WITH AN
EFFECTIVE DEEP BRAIN STIMULATION
IN SOME WAYS, RIGHT?
>> YES, CORRECT.
USUALLY
USUALLY
USUALLY PARKINSON'S STARTS WITH
TREATMENT WITH MEDICATIONS THAT
CAN ALSO PRODUCE THE DOPAMINE
EFFECT.
EFFECT.
EFFECT. BUT OVER TIME, THEY
BECOME LESS EFFECTIVE.
SO THEY
SO THEY
SO THEY CAN HAVE THESE SMALL ELECTRODES
IMPLANTED DEEP DOWN INTO THE
AREA OF THE BRAIN WHERE THOSE
BRAIN CELLS HAVE BEEN LOST.
AND
AND
AND BY
AND BY STIMULATING THAT AREA
ARTIFICIALLY, THEY CAN PRODUCE
THE EFFECT THAT THOSE BRAIN
CELLS SHOULD HAVE HAD IN THE
BEGINNING.
BEGINNING. AND REDUCE MOTOR
SYMPTOMS.
SYMPTOMS.
SYMPTOMS. >> WHAT DO WE WANT PEOPLE TO
KNOW ABOUT THIS DISEASE?
>> WELL, WE DO WANT PEOPLE TO
RECOGNIZE THE SYMPTOMS AND BE
ABLE TO SEE THEIR PHYSICIANS.
PARTICULARLY NEUROLOGISTS AND
MOVEMENT DISORDERS.
MOVEMENT DISORDERS. TO MAKE SURE
THEY GET THE RIGHT DIAGNOSIS.
AND THERE ARE EFFECTIVE
TREATMENTS BOTH FROM MEDICATION,
STIMULATION, CONTINUOUS
STIMULATION, CONTINUOUS INFUSIONS OF DOPAMINE THAT CAN
REALLY IMPROVE THEIR QUALITY OF
LIFE.
LIFE.
LIFE. MAYBE SLOW PROGRESSION AND
HELP THEM GET OVER THE SYMPTOMS
OF THIS DISORDER, EVEN THOUGH
THERE'S NOT A CURE.
>> I WAS GONNA ASK YOU.
WITHOUT
WITHOUT
WITHOUT A
WITHOUT A CURE, WHERE DO YOU FEEL WE'RE
AS FAR AS PROGRESS TOWARD A
CURE.
CURE.
CURE. OR
CURE. OR AT LEAST UNDERSTANDING
HOW PARKINSON'S COMES ABOUT AND
AFFECTS PEOPLE MOST?
>> WELL, I THINK WITH A LOT OF
THESE NEUROLOGICAL DISORDERS, I
THINK WE'VE COME A LONG WAY IN
TREATING THEM AND CONTROLLING
THE SYMPTOMS.
THE SYMPTOMS. TO THE POINT WHERE
IT DOESN'T REALLY IMPACT LIFE
MORTALITY VERY MUCH AND PEOPLE
CAN CONTINUE ON.
SO MAYBE NOT
FULLY REQUIRING ONGOING
TREATMENT, BUT THEY CAN LIVE
FULL LIVES.
FULL LIVES. >> WE CERTAINLY HOPE SO.
AND
AND
AND TODAY
AND TODAY ON WORLD PARKINSON'S DAY,
HOPEFULLY WE'RE GETTING CLOSER.