"Hi.
My name is Marta Zamabride and we are in Chiara Manzini Lab in the George Washington University.
We are working in Neuro-developmental diseases and the autism disease.
I'm from Spain.
From a little city, Pamplona.
In high school I started to be interested in biology in general.
I liked the nature and the human part of the biology.
I started doing my PhD on Alzheimer's Disease because my grandma has that so I was interested
in knowing how it works and if we can do something for them.
I started to look during my postdoc in Neuro-development disease.
Knowing what's happening with neuro degenerative diseases and Neuro-developmental diseases
I can have a bigger idea of what's going on in the brain.
Autism is a disease that usually children have.
Different problems with social interaction with people.
They are really anxious too related with other kids so they can't learn really good.
They can have memory deficit problems with the language so it's hard to them to be in
the social part of the community.
I usually do the biochemistry part so I analyze the proteins and the DNA.
So I usually use my samples to extract the protein and we do a technique which is the
western blot so we run the proteins and we can see the different size of each of them.
We can quantify the amount of protein that we have and see if the difference signal in
pathways are effective or not.
We are going to do a western blot so we are going to load proteins.
This is an electrolysis so we are going to use electricity to separate the different
proteins that we have in the sample.
The liquid is the running buffer here that we use.
The salts that we have in the buffer are going to allow the electricity to go through the
dell and separate the proteins.
For this one we used different tips with a filter.
When we are using DNA the pipettes can be contaminated so with this filter we avoid
contamination.
I collaborate with 2 postdocs here in the lab.
I work a lot with Adam because we have a project in common.
He's doing more the bio-microscopy and I'm more in the biochemistry part.
We have to collaborate everyday.
Its wonderful.
We can construct something bigger.
The problem with this kind of disease is the different models that we have.
I think we should focus more on the signaling.
Our model is going to be a new model of autism and in the long term we would like to treat
this model and can [...] that can help finally autism kids.
What we do in the lab is something really specific but finally is to help people.
If we can know what's going on in the brain and we can dissect what's the signaling pathways
of the brain we can know something to do in those pathways.
If you really like biology, you have to work hard to come here.
That's what I did.
If you really know what you want to do just follow and study a lot and you can be here.
Of course."