Q: Compare Septicemia, SIRS and Sepsis.
What are the differences?
A: Well, this gets very confusing.
That little [star] up there, this will work for a specialty CEU, I believe.
The American College of Chest Physicians and the Society of Critical Care Medicine have
established 4 different levels of sepsis.
The levels and symptoms are as follows:
1.
Systemic inflammatory response syndrome (SIRS) - you’ve probably heard of SIRS before?
And this gives you a list of things that a person has SIRS, signs and symptoms that we
have.
You’ve got hypothermia (your temperature is below 97°F) or a fever (a temperature
above 100°F), tachycardia (heart rate more than 100 beats per minute); tachypnea (rapid
breath, more than 20 breaths per minute) or hypocapnia (arterial CO2 less than 32 mmHg);
and leukopenia or leukocytosis (white blood count that is either too low or too high).
There is no confirmed infectious process in SIRS.
2.
What happens when you go to the next level?
Well, you have sepsis.
And sepsis is SIRS – everything that we just talked about before – in response to
a confirmed infectious process.
They see the infection; they know where it’s at.
3.
Severe sepsis – what happens when it graduates, I guess, you can call it – it includes the
dysfunction of one or more organs.
You get hypotension, you get hypoperfusion, and it’s going to affect one or more organs.
4.
It could turn into septic shock – sepsis with persistent arterial hypotension or hypoperfusion
despite adequate fluid resuscitation.
Last, septicemia, which is a serious, life-threatening infection that gets worse very quickly.
It can arise from infections throughout the body, including infections in the lungs, abdomen,
and urinary tract.
It may come before or at the same time as the infection is found.
What’s really scary is that older people sometimes suffer that and they’ll get like
a urinary tract infection and it just goes through the body and their body starts shutting
down organs.
Here is osteomyelitis, which is an infection of the bone.
Central nervous system would be meningitis.
You’ve heard stories about somebody that got sick, next thing you know they’ll do
a spinal tap, they got meningitis and they’re gone very quickly.
Endocarditis – infection of the heart muscles.
And, other tissues.
Here is a picture of a person that has septicemia and it had started in their legs and you can
see there’s a wound there.
There’s lots of swelling, there’s a rash usually and it will go very quickly.
Sepsis is a medical condition in which the immune system goes into overdrive, releasing
chemicals into the blood to combat an infection (microbes in the blood, urine, lungs, skin,
or other tissues) that trigger widespread inflammation (cellular injury in the body
tissues).
If the body is not able to regulate the immune response – which you can see this, this
redness and swelling and like I said, sometimes a rash – it then overwhelms normal blood
processes so the blood is not able to do its job.
The first mention of the word sepsis in a medical context was more than 2700 years ago
in the poems of Homer – which I thought was really cool and I would have loved to
have went and looked, a time to go in and find that.
The word derives from the Greek word sepein, meaning “to rot” – and that’s exactly
what happens.
Sepsis occurs in 1% to 2% of all the hospitalizations in the United States, affecting at least 750,000
persons and costing $17 billion per year to treat.
A term sometimes used for sepsis is “blood poisoning,” but there is no poison involved
in sepsis.
This is the most – how would I say it – benign picture that I can find, and my husband and
children thinks that I’m very morbid and like gory pictures; but just go in and Google
image sepsis, amazing what you can find and really sad conditions too for people on this
stuff can happen, just like that.