Jackie Shahin: Did you come across any results that indicate that blood sugar
issues can be triggered by poor digestion? There's some linkage in a
couple of different areas. There's a thing called haptoglobin 2. It's a
genetic variation of regular haptoglobin, not hemoglobin. Actually, haptoglobin
is in charge of cleaning up. Red blood cells last for about 90 days on average,
and then they blow up, and the hemoglobin gets spilled all over the artery. And
that's a problem because hemoglobin... what does it do? It carries oxygen, and oxygen
is by nature oxidative. So you've got this oxidative oxygen line. Haptoglobin
actually cleans that up. Whenever there's a problem, the body usually makes a
protein to deal with it, and the protein that deals with spilled hemoglobin is
haptoglobin. Now, there's a variation of haptoglobin called haptoglobin 2. If you
go back into the genetics, I'm so tempted to go down that bunny trail because it's
so interesting. Bottom line is folks that had that have a thing called zonulin,
and at the end of the day, believe it or not, have a thing called leaky gut. And
guess what stimulates that leaky gut and that zonulin? Gluten. Some of the different
gluten things like that. So believe it or not, the gluten-free diet
are... so many people thought was may have been sealing. They have been made up. It's
actually real, and believe it or not, they've gone into the genetics. They
traced the genetics back to a place just north of India what 20 generations back.
A significant preponderance in the tropic areas, very common gene at this
point. The allelic frequency... don't have to remember that term but we all have
two alleles. We've got a one from our mom, one from our dad, so the frequency of
that haptoglobin 2 gene is about 50%. It's very, very
common. So what does that got to do with digestion? Again, cause it's not on my
leaky gut but it's also very much associated with the risk of
cardiovascular disease, with diabetes. Because if you're haptoglobin is
not cleaning up your oxygen very well, it can cause some significant problems.
Pardon me if that was way too much of a bunny hole. Haptoglobin 2 is a major
unrecognized risk factor for those of us with prediabetes. I'll just leave it at
that.
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