Just wanted to cover this article. It makes a couple of significant statements.
The first one is that people with methylation problems it is a significant
issue and not just in terms of mental health. It's a significant increased risk
for diabetic eye disease. Another point that it makes is that you can do
something for diabetic eye disease, and it's a supplement as a supplement does
have a significant impact. It's a methylfolate supplement. So let's
get into the article and see a little bit more about what's going on.
It was in... I envisioned in 2019 I believe it was just a couple of months ago... July
2019 improving diabetic and hypertensive retinopathy with a medical food
containing L-methylfolate. A preliminary report. This is just a case series so
it's not a randomized clinical trial. There's not it's... not that advanced yet.
They're going and mention... they start out mentioning homocysteine. High
homocysteine is a marker for methylation problems. Vitamin D is... they mentioned
vitamin D is maybe playing a role as well. And so they went in and gave a
supplement that has methylfolate, the B vitamins methylated, and vitamin D in
addition to some AREDs components which... AREDS says you know age-related eye
disease, those are antioxidants. Methylation is this is a method of
achieving antioxidative a gave a a significant supplement one of them is
actually even a medical food. I won't get into the differences, but it has to do
with actually even requiring a prescription for it. Now
there are three different names. You'll see for this one is Eyefolate. One is
Restore Me. One is Restore V. Actually four names. Another name is Ocufolin.
L-methylfolate in it was 2.7 milligrams and 3.0 milligrams respectively and
vitamin D3 was 4500 international units. Each just below that 5000 that you see
is an average recommendation for most of us as you see on this slide. Yeah, it's
an AREDS combination vitamin C, D, E and the B complex as well as the zinc oxide
and zinc is found in a Reds as well as well as a couple of other things like
alpha lipoic acid, lutein, N-acetylcysteine, remember with a precursor
for glutathione. So again all looking at antioxidant activities, this shows the
the genetics of the individuals in this case series. As you see there, six of the
eight were MTHFR people with methylation problems the C677T
the R6770 variation, we also have some with A1298C. You don't need to know
those numbers obviously. I don't know, I keep tripping over them. I actually have
these by the way I've worked with a a genetics lab for about five years
and so was able to get a lot of my genetics at load and no costs for me so
I'm one of those people in that 40% category who has up to 70% challenges in
terms of the methylation. Again, one of the important ways of getting reduction
recharging after recharging those live embers that are lying around your
mitochondria, the furnaces of your cell lying there, oxidized. So again that's
where that comes from. But let's take a look at some of the
pictures. Obviously, you don't have to be an ophthalmologist to see the
improvement here. These red spots, these significant improvement there, I'll show
you a couple of others as well. Again, very obvious improvement in the eye. Now
one thing I would mention is that biologically the eye is behind what we
call the blood-brain barrier. So quite often we can't get medications or
supplements or other things beyond a thing called the blood-brain barrier. Why
does that matter? Well, think about the eye is very much a reflection of what's
going on in the brain or it can be. And the logic here is you know, does this
have any impact on the development of cognitive decline or a brain function? I
don't know the answer to that. But again, as you can see, we continue to go through
images. This is a cross-section of retinal tissue, and as you can see here
much improved thickness and density of the red retinal tissue. You'll see that
over and over in these videos is it the state of the absolute best research no
the absolute best research randomized clinical trials haven't been done yet on
those. Is it enough to make me think twice? Yeah, I'm starting to take this
very same supplement, and we'll be offering it at some point if we can if
we can get our program together. This may seem like a very unusual eye. These eyes
already had some surgery in terms of supporting that retina. That's what these
watches are. Now let's go on down and make another point that they made in
the study. They actually measured measured retinal blood flow velocity and
as you can see you got significant improvements after in both
arterioles (the tiniest arteries and the tiniest veins) after six months
of supplementation. So AREDS has been demonstrated many times all over the
world. The Eye Center in Miami has been a major center for investigating a
AREDS itself. This is something that's similar but not quite the same. It
includes AREDS as well as Smitha Foley. If you've made it this far, thank you
very much for your interests.
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